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Table 2 Insulin therapy and control of blood glucose levels.

From: Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial

Variable

Standard treatment (N = 250)

Intensive treatment (N = 254)

P value †

Administration of insulin (%)

118 (47)

246 (97)

< 0.001

Insulin dose (IU/day) *

12.5 ± 32.8

52.4 ± 53.3

< 0.001

Morning blood glucose (mg/dl) ‡ – Median. (Interquartile range)

148

122 to 180

117

101 to 140

< 0.001

Minimal blood glucose (mg/dl) – Median. (Interquartile range)

122

105 to 143

82

72 to 94

< 0.001

Maximal blood glucose (mg/dl) – Median. (Interquartile range)

172

141 to 215

162

140 to 193

< 0.001

Median blood glucose (mg/dl) – Median. (Interquartile range)

149

124.5 to 180

120

109.5 to 134

< 0.001

Number of blood glucose measurement per day *

5.9 ± 4

13 ± 5.5

< 0.001

Number of patients in which morning median blood glucose was in their preset range (%)

43 (17.2)

100 (39.4)

< 0.001

Hypoglycaemia ≤ 40 mg/dl (%)

2 (0.8)

21 (8.3)

< 0.001

  1. * Values presented as mean ± SD. Hypoglycaemia are number of patients with at least one episode over total number of patients per group.
  2. † P values were determined wit the use of Student's t-test, Mann-Whitney test or Chi-square test as appropriate.
  3. ‡ To convert the values for glucose to millimoles per litre, multiply by 0.05551.
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Critical Care

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