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Table 4 Comparison of statistical significance for patient risk variables between survivors and non-survivors

From: Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change

 

Survivors

Non-survivors

P value

SPRINT cohort

n = 310

n = 61

 

Average BG, mmol/L

6.1 (5.6–6.6)

5.9 (5.5–6.5)

0.55a

Maximum BG, mmol/L

9.9 (8.6–11.8)

10.4 (8.5–12.1)

0.62a

BG range, mmol/L

6.1 (4.7–8.1)

6.5 (5.0–8.8)

0.35a

APACHE II score

18.0 (14.0–22.0)

25.0 (18.0–30.3)

<0.01a

APACHE II risk of death

23% (12%-41%)

50% (26%-71%)

<0.01a

Average percentage goal feed

48% (0%-71%)

54% (29%-68%)

0.42a

Average hourly insulin, U/hour

2.7 (2.2–3.3)

2.5 (2.1–3.2)

0.65a

Diabetic history

56 (18.1%)

6 (9.8%)

0.12b

Retrospective cohort

n = 336

n = 77

 

Average BG, mmol/L

7.5 (6.6–8.4)

7.3 (6.6–8.3)

0.83a

Maximum BG, mmol/L

10.5 (9.4–12.6)

11.3 (10.0–13.6)

0.04a

BG range, mmol/L

5.8 (3.8–8.6)

6.8 (4.7–9.5)

0.05a

APACHE II score

18.0 (15.0–22.0)

24.0 (18.8–29.0)

<0.01a

APACHE II risk of death

25% (13%-43%)

51% (23%-67%)

<0.01a

Average hourly insulin, U/hour

0.8 (0.0–1.7)

1.0 (0.5–1.5)

0.33a

Diabetic history

58 (17.3%)

13 (16.9%)

0.94b

  1. Statistical significance was tested for average, maximum and range of blood glucose, APACHE II score, average feed rate, and diabetic history between SPRINT intensive care unit survivors and mortalities. Data are expressed as number (percentage) or per-patient median (interquartile range) where appropriate. aMann-Whitney U test; bchi-square test. APACHE, Acute Physiology And Chronic Health Evaluation; BG, blood glucose concentration; SPRINT, Specialised Relative Insulin Nutrition Tables.