From: The histopathology of septic acute kidney injury: a systematic review
Study | Cause | Acute kidney injury definition | Method | Cases of AKI/number of patients (%) | Acute tubular necrosis (%) |
---|---|---|---|---|---|
Hotchkiss and colleagues [10] | Sepsis/septic shock | Serum creatinine >2 mg/dl and urine output <20 ml/kg/hour × 6 hours | Postmortem | 12/20 (60) | 1 (5) |
Sato and colleagues [13] | Sepsis | Not available | Postmortem | 6/6 (100) | 1 (17) |
Mustonen and colleagues [9] | Sepsis/shock/hypovolemia | Not available | Biopsy | 57/57 (100) | 4 (7) |
Rosenberg and colleagues [12] | Sepsis | Serum creatinine >3.5 mg/dl and urine/plasma osmolality >1 | Biopsy | 1/1 (100) | 0 (0) |
Zappacosta and Ashby [14] | Sepsis | Not available | Biopsy | 1/1 (100) | 0 (0) |
Diaz de Leon and colleagues [11] | Severe sepsis | Serum creatinine, urine output, urine/plasma osmolality (not specified) | Biopsy | 107/332 (32) | 20 (50)a |