The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The Netherlands

Table 2 Demographic data, variables and outcome data; comparisons of sepsis patients with EGDT study [8] data

Variable	Present cohort (n = 263)	Sepsis (n = 125)	EGDT study (n = 263)	p Value^a,b
Age (years)	67.3 ± 14.2	68.9 ± 13.5	65.7 ± 17.2	0.01*
Female (%)	41	38	49.4
Male (%)	59	62	50.6
Heart rate (beats/min)	107 ± 27	115 ± 26	115 ± 29	1.0
CVP (mmHg)	9.8 ± 5.4	10.8 ± 4.9	5.7 ± 8.5	< 0.01*
MAP (mmHg)	58 ± 16	60 ± 13	75 ± 25	< 0.01*
ScvO₂ (%)	72.0 ± 12.3	74.0 ± 10.2	48.9 ± 12.3	< 0.01*
Lactate (mmol/l)	3.3 ± 3.3	2.7 ± 2.2	7.3 ± 4.6	< 0.01*
Arterial pH	7.33 ± 0.12	7.35 ± 0.10	7.32 ± 0.18	0.42
Hematocrit (%)	31.0 ± 7.0	30.3 ± 6.9	34.7 ± 8.5	< 0.01*
APACHE II score	21.5 ± 8.5	20.9 ± 7.3	20.9 ± 7.2	1.0
SOFA score	9.5 ± 3.6	9.6 ± 3.0
In-hospital mortality (%)	31.0	26.0
Standard therapy			46.5
EGDT			30.5

Data are presented as means ± SD. ^aUnpaired t test; ^bsepsis subgroup vs EGDT study. *Statistically significant difference. APACHE II, Acute Physiology, Age and Chronic Health Evaluation; CVP, central venous pressure; EGDT, early goal-directed therapy; MAP, mean arterial pressure; ScvO₂, central venous oxygen saturation; SOFA, Sequential Organ Failure Assessment.

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