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Table 1 Baseline characteristics at intensive care unit admission stratified by study period

From: Intensive insulin therapy and mortality in critically ill patients

Clinical characteristic

Period I

(n = 2,366)

1 Mar 01 to 28 Feb 02

Period II

(n = 3,322)

1 Mar 02 to 30 Jun 03

Period III

(n = 4,786)

1 Jul 03 to 28 Feb 05

Age in years, mean ± SD

51.1 ± 18.5

51.6 ± 19.1

51.6 ± 19.0

Male gender, n (%)

1,467 (62.0)

2,071 (62.4)

3,044 (63.9)

Race or ethnic group, n (%)a

   

   Native American

70 (2.96)

62 (1.87)

105 (2.20)

   Asian

142 (6.00)

220 (6.63)

294 (6.17)

   African-American

224 (9.47)

291 (8.77)

369 (7.74)

   Caucasian

1,651 (69.78)

2,310 (69.60)

3,422 (71.77)

   Hispanic

91 (3.85)

156 (4.70)

228 (4.78)

   Unknown

188 (7.95)

283 (8.52)

350 (7.34)

History of diabetes, n (%)

   

   Type I

64 (2.7)

68 (2.1)

77 (1.6)

   Type II

211 (8.92)

367 (11.1)

574 (12.0)

History of chronic disease, n (%)b

74 (3.2)

95 (2.9)

137 (2.9)

SAPS II, mean ± SDc

39.1 ± 18.1

39.3 ± 18.9

37.2 ± 18.4

APS III, mean ± SDd

53.1 ± 21.8

53.1 ± 23.3

50.5 ± 23.3

Trauma patients, n (%)

857 (36)

1,203 (36)

1,920 (40)

Injury Severity Score, mean ± SD

21.2 ± 10.9

20.8 ± 11.1

20.7 ± 10.6

Type of admission, n (%)

   

   Surgical admission

1,440 (60.9)

2,003 (60.3)

3,084 (64.7)

   Medical admission

926 (39.1)

1,319 (39.7)

1,684 (35.3)

Admitting service, n (%)

n = 2,366

n = 3,314

n = 4,745

   Surgical ICU

759 (32.1)

1,061 (32.0)

1,604 (33.8)

   Medical ICU

756 (31.9)

1,025 (30.9)

1,303 (27.5)

   Coronary ICU

170 (7.19)

270 (8.2)

350 (7.4)

   Neurosurgical ICU

607 (25.7)

871 (26.3)

1,335 (28.1)

   Burn ICU

74 (3.1)

87 (2.6)

153 (3.2)

Weight in kilograms, mean ± SD

83.0 ± 24.9

84.6 ± 26.0

84.5 ± 25.5

Admission glucose in mg/dL, mean ± SD

162.5 ± 88.9

161.3 ± 82.5

152.1 ± 69.1

Mechanical ventilation, n (%)

1,424 (60.2)

1,878 (56.5)

2,578 (54.1)

  1. aRace or ethnic group was assigned on the basis of hospital record. bChronic disease defined according to Simplified Acute Physiology Score (SAPS) II criteria. cSAPS II can range from 0 to 162, with higher scores indicating a higher risk of death. dAPS is the acute physiology score of the APACHE (Acute Physiology and Chronic Health Evaluation) III score; it can range from 0 to 251, with higher scores indicating a higher risk of death. ICU, intensive care unit; SD, standard deviation.