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Table 2 Analysis of anions by means of capillary electrophoresis

From: Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions

 

Time point of measurement

 

Baseline

Shock

Immediately after therapy

30 minutes after therapy

60 minutes after therapy

180 minutes after therapy

Acetate, mEq/L

2.4 ± 0.5

4.4 ± 0.9

5.8 ± 0.4a

4.8 ± 0.5

3.9 ± 1.0

2.3 ± 0.5

β-HOB, mEq/L

1.7 ± 0.7

2.0 ± 0.3

1.7 ± 0.2

2.6 ± 1.2

2.9 ± 1.3

2.6 ± 0.9

Sulfate, mEq/L

1.4 ± 0.1

1.5 ± 0.1

1.4 ± 0.1

1.4 ± 0.1

1.3 ± 0.1

1.3 ± 0.1

Citrate, mEq/L

0.5 ± 0.1

2.4 ± 0.7a

1.2 ± 0.2

1.3 ± 0.3

1.2 ± 0.2

1.5 ± 0.4

Fumarate, μEq/L

ND

6.2 ± 1.3

6.7 ± 2.2

4.1 ± 1.3

3.7 ± 1.5

5.0 ± 1.3

α-KG, μEq/L

ND

35.3 ± 10.4

25.3 ± 7.9

28.8 ± 4.5

27.8 ± 4.1

20.8 ± 8.5

Urate, μEq/L

15.1 ± 1.1

55.9 ± 14.4a

32.7 ± 4.1a

26.5 ± 8.5

18.3 ± 2.9

19.7± 6.1

  1. Data are presented as mean ± standard error of the mean (n = 4 to 8). ap < 0.05 with respect to baseline. α-KG, serum concentration of α-ketoglutarate; β-HOB, serum concentration of β-hydroxybutyrate; acetate, serum concentration of acetate; citrate, serum concentration of citrate; fumarate, serum concentration of fumarate; ND, not detectable; sulfate, serum concentration of sulfate; urate, serum concentration of urate.