Table 1 Excluded studies examining antifungal prophylaxis in adult non-neutropenic patients (n = 24)
Reference | Year | Endpoint | Exclusion | Design |
|---|---|---|---|---|
Stoutenbeek et al. [41] | 1984 | SDD in ICU patients | Only yeast as percentage of cultures | Cohort |
Slotman et al. [42] | 1988 | Ketoconazole prophylaxis in ALI/ARDS | No yeast scored | RCT |
Flaherty et al. [43] | 1990 | SDD in ICU patients | No yeast scored | RCT |
Godard et al. [44] | 1990 | SDD in ICU patients | No yeast scored (+ no control group) | RCT |
Rodriguez-Roldán et al. [45] | 1990 | SDD in ICU patients | No yeast scored | RCT |
Tetteroo et al. [46] | 1990 | SDD in oesophageal resection | No yeast scored | RCT |
Gastinne et al. [47] | 1992 | SDD in ICU patients | No yeast scored | RCT |
Jacobs et al. [48] | 1992 | SDD in ICU patients | No yeast scored | RCT |
Rocha et al. [49] | 1992 | SDD in ICU patients | No yeast scored | RCT |
Korinek et al. [50] | 1993 | SDD in neurosurgical ICU patients | Only yeast as percentage of cultures | RCT |
Yu and Tomasa [51] | 1993 | Ketokonazole prophylaxis in ARDS | No yeast scored | RCT |
Misset et al. [52] | 1994 | SDD in ICU patients | No control group | RCT |
Sorkine et al. [53] | 1996 | Amphotericin B treatment in Candida sepsis | No control group | RCT |
Lingnau et al. [54] | 1997 | SDD in multiple trauma patients | No yeast scored | RCT |
Palomar et al. [55] | 1997 | SDD in ICU patients | No yeast scored | RCT |
Safran and Dawson [56] | 1997 | Fluconazole prophylaxis in SICU patients | Retrospective (+ no control group) | Cohort |
Schardey et al. [57] | 1997 | SDD in total gastrectomy | Only yeast as percentage of cultures | RCT |
Sánchez GarcÃa et al. [58] | 1998 | SDD in ICU patients | Only yeast as percentage of cultures | RCT |
ARDS network [59] | 2000 | Ketoconazole prophylaxis in ALI/ARDS | No yeast scored | RCT |
Pneumatikos et al. [60] | 2002 | Subglottal decontamination | No yeast scored | RCT |
De Waele et al. [61] | 2003 | Fluconazole prophylaxis in pancreatitis | Retrospective | Cohort |
Swoboda et al. [62] | 2003 | Fluconazole prophylaxis in SICU patients | Retrospective | Cohort |
Magill et al. [63] | 2004 | Fluconazole prophylaxis in SICU patients | No yeast scored | RCT |
Shan et al. [64] | 2006 | Early presumptive therapy in GI surgery | Retrospective | Cohort |