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Table 1 Part 1. Patient characteristics and associations with inflammatory response after cardiopulmonary bypass

From: Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trial

Variables

Inflammatory response (n = 34)

No inflammatory response (n = 131)

P value

Age, years

61 ± 12

61 ± 13

0.97

Gender

   

   Male, number (percentage)

24 (70)

88 (67)

0.70

   Female, number (percentage)

10 (30)

43 (33)

0.70

Body mass index, kg/m2

28.5 ± 5

27.5 ± 4.2

0.20

Parsonnet score

13.6 ± 9.2

12.1 ± 6.8

0.35

Comorbidity

   

   Renal disease, number (percentage)

4 (11)

8 (6)

0.26

   Diabetic status, number (percentage)

12 (35)

44 (34)

0.85

   Angiotensin-converting enzyme inhibitors, number (percentage)

10 (29)

45 (34)

0.58

Cardiac intervention

   

   Coronary, number (percentage)

19 (56)

81 (62)

0.20

   Valvular, number (percentage)

9 (26)

41 (31)

0.58

   Both, number (percentage)

6 (17)

9 (7)

0.051

   Reintervention, number (percentage)

2 (6)

6 (5)

0.75

Surgical data

   

   Total cardiopulmonary bypass time, minutes

101 ± 33

93 ± 33

0.20

   Aortic clamping time, minutes

61.6 ± 27.3

54 ± 22.8

0.11

   Tranexamic acid, number (percentage)

8 (26)

78 (60)

<0.01

   No antifibrinolytics, number (percentage)

26 (76)

53 (40)

0.44

   Intensive care unit stay, days

7.8 ± 6.4

3.2 ± 1.7

<0.01

   Hospital stay, days

17.6 ± 20.5

9.1 ± 6.2

<0.01

  1. Values are expressed as mean ± standard deviation.