Intervention | Effecta | Supporting evidenceb |
---|---|---|
Nonpharmacologic | Â | Â |
   Multicomponent strategy | Prevention | Non-ICU clinical trials [56,58] |
   Geriatrics consultation | Prevention | Non-ICU clinical trials [57] |
   Reduced benzodiazepine use | Prevention | Prospective ICU cohort studies [40] |
Pharmacologic | Â | Â |
   Haloperidol | Both | Placebo-controlled, randomized, non-ICU trial [62] |
   Olanzapine | Treatment | Non-randomized ICU trial [63] |
   Adequate analgesia | Prevention | Prospective non-ICU cohort studies [45] |
   Dexmedetomidine | Prevention | Randomized ICU trials [68,69] |