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Figure 1 | Critical Care

Figure 1

From: Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study

Figure 1

Description of urine collection procedures and use of urine specimens with reference to analytic time points. (a) Overall urine collection procedure. The image shows that study enrollment began shortly after initiation of ventilation and that urine was collected once per day for up to 4 days if possible. (b) Acute kidney injury (AKI) urine specimens collected before AKI development were used for assessment of urine neutrophil gelatinase-associated lipocalin (uNGAL) for early detection of AKI. (c) AKI urine specimens collected within 24 hours of AKI by pRIFLE (pediatric modified Risk, Injury, Failure, Loss, End Stage Kidney Disease) criteria were used to evaluate uNGAL as a marker of severity of renal injury. day 0, the first day the patient attained AKI; PICU, pediatric intensive care unit; pRIFLEmax, the worst pRIFLE stratum attained; SCr, serum creatinine; uNGAL, urine neutrophil gelatinase-associated lipocalin.

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