Bolus group (n = 23) | Infusion group (n = 22) | p value | |
---|---|---|---|
Age (years) | 61 ± 17 | 60 ± 16 | 0.732 |
APACHE II score | 22.7 ± 5.6 | 22.5 ± 7.9 | 0.950 |
SAPS II | 51.5 ± 11.3 | 52.2 ± 14.6 | 0.860 |
SOFA score | 10.0 ± 2.1 | 10.3 ± 2.4 | 0.707 |
PaO2/FiO2 ratio (mm Hg) | 193 ± 110 | 176 ± 75 | 0.532 |
Cardiac index (l/minute per m2) | 3.8 ± 1.7 | 3.6 ± 1.5 | 0.555 |
Mean arterial pressure (mm Hg) | 62 ± 7.5 | 65 ± 7.9 | 0.188 |
Systemic vascular resistance (dyn·s/cm5) | 623 ± 221 | 731 ± 254 | 0.158 |
SvO2 (percentage) | 61 ± 7.6 | 64 ± 12 | 0.462 |
Hemoglobin (g/l) | 106 ± 22 | 105 ± 19 | 0.890 |
Leukocyte count (109/l) | 14.1 ± 9.2 | 9.6 ± 7.7 | 0.091 |
Platelet count (109/l) | 180 ± 103 | 141 ± 92 | 0.191 |
Plasma C-reactive protein (mg/l) | 223 ± 115 | 197 ± 99 | 0.428 |
Serum lactate (mmol/l) | 2.3 ± 1.6 | 2.8 ± 1.9 | 0.471 |
Norepinephrine dose (μg/kg per minute) | 0.22 ± 0.12 | 0.19 ± 0.16 | 0.579 |
ICU mortality, n (percentage) | 4 (17%) | 7 (29%) | 0.494 |