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Table 1 Prognosis of a comatose patient

From: Bench-to-bedside review: Brain dysfunction in critically ill patients – the intensive care unit and beyond

Primary assessment

 

   Glasgow Coma Scale <8?

Patient is comatose

   No response to environment?

 

At 24 hours

 

   Clinical examination

 

Absent pupillary response?

Probability of a poor outcome, 97%

Absent motor response?

Probability of a poor outcome, 97%

   Somatosensory evoked potentials, absent N20 signal bilaterally

Probability of a poor outcome, 100%

   Serum neuron-specific enolase ≥33 μg/l

Probability of a poor outcome, 100%

At 72 hours

 

   Clinical examination

 

Absent motor response?

Probability of a poor outcome, 97%

   Somatosensory evoked potentials, absent N20 signal bilaterally

Probability of a poor outcome, 100%

   Serum neuron-specific enolase ≥33 μg/l

Probability of a poor outcome, 100%

   Electroencephalography, isoelectric or burst-suppression

Probability of a poor outcome, 100%

  1. 'Poor outcome' is defined as death or persistent coma 1 month later [5,13].