Clinical feature | Cause of acute tubular necrosis | ||
---|---|---|---|
Ischaemic (n = 265) | Mixed (n = 201) | Nephrotoxic (n = 58) | |
Multiorgan failure | 122 (46%)† | 110 (55%)‡ | 4 (7%) |
Respiratory failure | 230 (87%)† | 193 (96%)‡* | 40 (69%) |
Shock | 220 (83%)† | 175 (87%)‡ | 8 (14%) |
Hepatic failure | 37 (14%)† | 16 (8%) | 2 (3%) |
Coma | 106 (40%)† | 68 (34%) | 12 (21%) |
Infection | 143 (54%) | 149 (74%)‡* | 31 (53%) |
Gastrointestinal bleeding | 45 (17%)† | 24 (12%) | 4 (7%) |
Oliguria | 130 (49%) | 116 (58%)‡ | 22 (38%) |
Hypervolaemia | 37 (14%) | 40 (20%) | 6 (10%) |
Acidosis | 193 (73%) | 163 (81%)‡ | 37 (64%) |
Admission creatinine (mg/dl) | 1.98 ± 0.88† | 1.81 ± 0.88 | 1.63 ± 0.85 |
Peak creatinine (mg/dl) | 3.24 ± 1.59 | 3.41 ± 1.50‡ | 2.78 ± 1.03 |
Discharge creatinine (mg/dl) | 2.70 ± 1.47 | 2.98 ± 1.56* | 1.96 ± 0.96 |
Dialysis | 24 (9%) | 34 (17%)* | 4 (7%) |
Mortality | 175 (66%)† | 127 (63%)‡ | 22 (38%) |