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Table 1

From: The impact of eligibility criteria on enrollment in ICU sepsis clinical trials

 

Study A

Study B

Study C

 

(phase III)

(phase III)

(phase II)

Eligible (% sepsis)

117 (20.9)

40 (7.1)

116 (20.7)

Excluded (% of eligible)

85 (72.6)

30 (75.0)

108 (93.1)

   met study specific excl.

[48]

[19]

[88]

   hopeless prognosis

[32]

[8]

[17]

   other study

 

[5]

[3] [3]

Truly eligible (% eligible)

32 (27.3)

10 (25)

8 (6.8)

Enrolled

27

6

4

Recruitment efficiency

84%

60%

50%