Figure 1From: New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated)The protein C pathway: modulation of thrombin generation and cell signaling. APC, activated protein C; EPCR, endothelial protein C receptor; PAI-1, plasminogen activator inhibitor 1; PAR, protease-activated receptor; Rac, ras-related protein; Rho, ras-homolog; S-1 P-1; sphingosine 1 phosphate 1-receptor.Back to article page