Time course of endothelial damage in septic shock: prediction of outcome

Table 3 Predictive parameters determined by the area under the receiver operating characteristics curve (AUC)

Time point	AUC	95% confidence interval	P
Baseline
IL-8	0.777	0.619–0.935	0.004
IL-6	0.648	0.462–0.834	0.14
sELAM-1	0.600	0.400–0.800	0.30
sICAM-1	0.548	0.360–0.735	0.622
Third day
IL-8	0.133	0.402–0.923	0.25
IL-6	0.727	0.501–0.953	0.087
sELAM-1	0.808	0.599–1.017	0.02
sICAM-1	0.677	0.427–0.927	0.18
Fourth day
IL-8	0.775	0.529–1.021	0.05
IL-6	0.737	0.504–0.971	0.09
sELAM-1	0.847	0.631–1.064	0.02
sICAM-1	0.694	0.433–0.956	0.18

sELAM-1, soluble endothelial-linked adhesion molecule 1; sICAM-1, soluble intercellular adhesion molecule 1.

ISSN: 1364-8535