Table 1
| Â | Group control | Group 2: | Group 3: | Group 4: | Group 5: |
|---|---|---|---|---|---|
|  |  | MPS 10 mg/kg | MPS 10 mg/kg | MPS 2 × 10 mg/kg | MPS 30 mg/kg |
| Â | Â | (h-4) | (IA) | (h-12 + IA) | (h-4) |
Tropo-T (ng/ml) | 0.07 ± 0.2 | 0.10 ± 0.06 | 0 ± 0 | 0.04 ± 0.04 | 0.07 ± 0.3 |
(t=0) mean ± SEM |  |  |  |  |  |
Tropo-T (ng/ml) | 6.2 ± 2.0 | 1.4 ± 0.5* | 5.0 ± 1.5 | 5.8 ± 1.9 | 1.0 ± 0.2** |
(t=1) mean ± SEM |  |  |  |  |  |
Age (years) | 60 ± 3 | 63 ± 2 | 62 ± 5 | 64 ± 2 | 64 ± 2 |
Weight (kg) | 86 ± 4 | 79 ± 2 | 79 ± 3 | 80 ± 3 | 82 ± 3 |
CPB (min) | 95.3 ± 6.1 | 95.0 ± 7.5 | 95.0 ± 7.5 | 110.3 ± 4.4 | 104.5 ± 7.6 |
Ao cl (min) | 65.6 ± 6.3 | 59.3 ± 5.9 | 64.6 ± 5.7 | 84.3 ± 4.6 | 59.2 ± 4.8 |
No. of grafts (n) | 3.0 ± 0.2 | 2.6 ± 0.2 | 2.7 ± 0.3 | 3.5 ± 0.3 | 2.6 ± 0.2 |