Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS

Table 1 The sepsis-related organ failure assessment (SOFA) score evaluation system of multiple organ dysfunction [12]. Six organ systems are evaluated as a scale of 1-4 each. The arithmetical sum of these six is the value of the SOFA score.

Score points	1	2	3	4
Respiration
PaO₂/FiO₂	< 400	< 300	< 200	< 100
			with respiratory support	with respiratory support
Coagulation
Platelets ×10³/mm³	< 150	< 100	< 50	< 25
Liver
Bilirubin mg/dl	1.2–1.9	2.0–5.9	6.0–11.9	> 12.0
Cardiovascular
Hypotension^a	MAP < 70mmhg	Dopamine ≤ 5 or	Dopamine > 5 or	Dopamine > 15 or
		dobutamine in any dose	epinephrine ≤ 0.1 or	epinephrine > 0.1 or
			norepinephrine ≤ 0.1	norepinephrine > 0.1
Central nervous system
Glasgow Coma Scale	13–14	10–12	6–9	< 6
Renal
Creatinine mg/dl	1.2–1.9	2.0–3.4	3.5–4.9	5.0
or urine output			or < 500ml/24h	or < 200ml/24h

^aAdrenergic agents administered for at least 1 h (dosesare given in μ g/kg/min). MAP, mean arterial pressure.

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