Parameter | Remifentanil (n = 47) | Fentanyl (n = 22) | Morphine (n = 28) |
---|---|---|---|
Median time on mechanical ventilation during the treatment period, h (range) | 24.83 (12.5–110.2) | 24.08 (16.4–70.0) | 37.04 (17.8–98.2) |
Hazard ratio relative to comparator | 1.21 | 0.71 | |
95% CI | 0.70, 2.10 | 0.43, 1.18 | |
P | 0.500 | 0.188 | |
Median time from the start of the extubation process until actual extubation, h (range) | 1.00 (0.0–97.2) | 0.68 (0.0–5.6) | 1.93 (0.0–96.2) |
Hazard ratio relative to comparator | 1.23 | 0.42 | |
95% CI | 0.70, 2.13 | 0.25, 0.71 | |
P | 0.474 | 0.001 | |
Median time from the start of extubation process until ICU discharge, h (range) | 43.50 (2.4–150.0) | 42.90 (2.2–120.6) | 49.63 (3.7–144.2) |
Hazard ratio relative to comparator | 1.34 | 0.98 | |
95% CI | 0.76, 2.37 | 0.56, 1.70 | |
P | 0.316 | 0.928 |