Table 2 Demographic and case mix data for all patients
| Â | All patients | No AKI | AKI | P value |
|---|---|---|---|---|
|  | Mean ± sd | Mean ± sd | Mean ± sd |  |
Age (years) | 60.1 ± 15.3 | 59.2 ± 15.1 | 62.2 ± 15.7 | 0.214 |
Female sex | 86 (44%) | 59 (44%) | 27 (46%) | 0.791 |
Weight (kg) | 66.6 ± 11.0 | 66.8 ± 11.4 | 66.0 ± 10.2 | 0.619 |
Specialty code prior to unit admission ( % ) | Â | Â | Â | Â |
Accident and Emergency | 22 (11%) | 13 (10%) | 9 (15%) | 0.05 |
Medicine | 50 (26%) | 38 (28%) | 12 (20%) | |
Surgery | 76 (39%) | 46 (34%) | 30 (51%) | |
Trauma | 12 (6.2%) | 11 (8%) | 1 (2%) | Â |
Other | 34 (17.5%) | 27 (20.0%) | 7 (11.9%) | Â |
ICU admission | Â | Â | Â | Â |
APACHE II | 14.0 ± 5.5 | 12.8 ± 5.3 | 16.7 ± 5.2 | <0.001 |
Creatinine (mg/dL) | 80.8 ± 29.1 | 68.2 ± 18.9 | 109.4 ± 28.0 | <0.001 |
pNGAL on admission (ng/L) | 209 (141, 389) | 168.0 (121.3, 274.3) | 436.0 (240.0, 797.0) | <0.001 |
uNGAL on admission (ng/L) | 53 (16, 283) | 34.50 (11.5, 107.75) | 342.00 (61.5, 1,280) | <0.001 |
Urine output (mL/hour) | 67 (40, 100) | 70 (45, 100) | 60 (36, 90) | 0.098 |
MAP (mmHg) | 78.6 ± 16.7 | 80.54 ± 16.78 | 74.12 ± 15.82 | 0.012 |
Mechanical ventilation (%) | 84 (43%) | 58 (43%) | 26 (44%) | 0.886 |
Vasopressors (%) | 54 (28%) | 29 (21%) | 25 (42%) | 0.003 |
Sepsis (%) | 15 (8%) | 7 (5%) | 8 (14%) | 0.136 |
RRT in first 24 hours (%) | 2 (1%) | 0 (0%) | 2 (3%) | 0.093 |
Nephrotoxic agents ( % ) | Â | Â | Â | - |
Radio contrast dye | 36 (19%) | 19 (14%) | 17 (29%) | Â |
ACE inhibitor | 55 (28%) | 37 (27%) | 18 (31%) | Â |
Diuretics | 37 (19%) | 22 (16%) | 15 (25%) | Â |
ARBs | 10 (5%) | 5 (4%) | 5 (8%) | Â |
NSAIDs | 9 (5%) | 7 (5%) | 2 (3%) | Â |
Cyclosporin | 1 (1%) | 0 | 1 (2%) | Â |
None | 104 (54%) | 76 (56%) | 28 (47%) | Â |
Outcome | Â | Â | Â | Â |
Hospital mortality (%) | 15 (8%) | 5 (4%) | 10 (17%) | 0.001 |