From: Application of heart-rate variability in patients undergoing weaning from mechanical ventilation
Characteristics | Successful extubation | Extubation failure | P value |
---|---|---|---|
(n = 64) | (n = 13) | ||
Age, years | 64 ± 19 | 71 ± 15 | 0.247 |
 ≧65 years | 36 (56) | 9 (69) | 0.387 |
Male sex | 45 (70) | 9 (70) | 0.999 |
Body mass index | 22 ± 5 | 21 ± 3 | 0.373 |
APACHE II | 17 ± 6 | 19 ± 7 | 0.303 |
Comorbidities | |||
 Cerebrovascular disease | 14 (22) | 2 (15) | 0.725 |
 COPD | 16 (25) | 3 (23) | 0.999 |
 Heart failure | 3 (5) | 0 (0) | 0.999 |
 Liver cirrhosis | 3 (5) | 1 (8) | 0.530 |
 End-stage renal disease | 4 (6) | 2 (15) | 0.266 |
 Diabetes mellitus | 23 (36) | 3 (23) | 0.525 |
 Hypertension | 26 (41) | 4 (31) | 0.506 |
 Coronary artery disease | 5 (8) | 0 (0) | 0.582 |
Cause of acute respiratory failure | |||
 Pneumonia | 29 (45) | 5 (39) | 0.650 |
 Sepsis | 13 (20) | 2 (15) | 0.999 |
 Acute exacerbation of COPD | 2 (3) | 1 (8) | 0.430 |
 Gastrointestinal bleeding | 8 (13) | 2 (15) | 0.674 |
 Lung edema | 4 (6) | 0 (0) | 0.999 |
 Neurologic disease | 4 (6) | 2 (15) | 0.266 |
 Others | 4 (6) | 1 (8) | 0.999 |
Time to first SBT, hours | 102 ± 109 | 64 ± 55 | 0.221 |
Medications | |||
 β2 agonist | 22 (34) | 6 (46) | 0.530 |
 Anticholinergic | 17 (27) | 5 (39) | 0.502 |
 ACEI/ARB | 7 (11) | 1 (8) | 0.999 |
 CCB | 24 (38) | 3 (23) | 0.525 |
 β blocker | 9 (14) | 2 (15) | 0.999 |