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Figure 2 | Critical Care

Figure 2

From: Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study

Figure 2

ROC curves of TAT, PAI-1 and PC activity for prediction of overt DIC. Area under the receiver operating characteristic curve (AUROC) for thrombin-antithrombin complex (TAT), 0.77 (95% CI, 0.64 to 0.86), plasminogen activator inhibitor-1 (PAI-1), 0.87 (0.78 to 0.92), protein C (PC), 0.85 (0.76 to 0.91), and combination of these biomarkers are described. Combination of TAT, PAI-1 and PC was superior to each marker alone (AUROC, 0.95 (vs. TAT, P = 0.0004; vs. PAI-1, P = 0.033; vs. PC, P = 0.025)).

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Critical Care

ISSN: 1364-8535