Group | M 0 | M 1 | M 2 | M 3 | M 4 | M 5 | M 6 | M 7 | M 8 | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hemoglobin (g/dl) | TEA | 8.8 ± 0.6 | 8.6 ± 0.6 | 8.2 ± 0.6 | 8.7 ± 0.7 | 9.1 ± 0.9 | 8.6 ± 0.5 | 8.6 ± 0.5 | 8.4 ± 0.7 | 8.2 ± 0.8 | 9.7 ± 0.8 | 9.6 ± 1.4 | 9.3 ± 1.2 | 9.2 ± 1.4 | 9.4 ± 1.2 | 9.3 ± 1.2 | 8.6 ± 1.4 |
Controll | 8.6 ± 0.5 | 8.7 ± 0.5 | 8.1 ± 0.6 | 8.5 ± 0.4 | 8.7 ± 0.5 | 8.4 ± 0.7 | 8.5 ± 0.9 | 8.0 ± 0.9 | 7.8 ± 0.6 | 9.5 ± 0.5 | 9.4 ± 1.2 | 9.4 ± 0.9 | 9.3 ± 0.4 | 9.3 ± 1.6 | 10.0 ± 0.7 | 9.5 ± 1.0 | |
Leucocytes (10 9 /L) | TEA | 9.2 ± 3.0 | 8.7 ± 3.9 | 10.8 ± 4.0 | 9.4 ± 4.5 | 11.9 ± 4.4 | 11.8 ± 3.4 | 11.0 ± 3.0 | 10.5 ± 3.4 | 9.5 ± 4.3 | 11.0 ± 4.0 | 15.1 ± 4.6 | 18.8 ± 6.8 | 17.0 ± 7.1 | 23.4 ± 7.4 | 24.1 ± 7.6 | 23.5 ± 7.2 |
Controll | 9.0 ± 3.4 | 11.3 ± 3.2 | 12.8 ± 5.3 | 11.9 ± 2.4 | 13.3 ± 3.1 | 12.8 ± 3.3 | 12.4 ± 3.8 | 11.6 ± 3.4 | 9.8 ± 4.3 | 11.4 ± 3.5 | 17.9 ± 4.6 | 18.2 ± 6.6 | 17.7 ± 3.9 | 21.5 ± 6.7 | 25.0 ± 2.4 | 21.2 ± 6.3 | |
Thrombocytes (10 9 /L) | TEA | 279 ± 97 | 196 ± 40 | 263 ± 72 | 176 ± 13 | 202 ± 38 | 191 ± 15 | 198 ± 19 | 186 ± 29 | 266 ± 97 | 356 ± 148 | 337 ± 103 | 380 ± 140 | 417 ± 174 | 445 ± 191 | 408 ± 178 | 403 ± 151 |
Control | 322 ± 97 | 240 ± 41 | 296 ± 100 | 251 ± 32 | 237 ± 42 | 250 ± 40 | 233 ± 20 | 211 ± 18 | 272 ± 100 | 366 ± 99 | 321 ± 94 | 333 ± 63 | 361 ± 100 | 423 ± 164 | 353 ± 175 | 408 ± 101 | |
PT (seconds) | TEA | 108 ± 9 | 110 ± 5 | 107 ± 8 | 112 ± 7 | 110 ± 6 | 113 ± 4 | 110 ± 7 | 110 ± 9 | 107 ± 10 | 94 ± 10 | 112 ± 8 | 109 ± 15 | 102 ± 12 | 98 ± 13 | 98 ± 11 | 94 ± 11 |
Control | 115 ± 8 | 108 ± 5 | 105 ± 23 | 107 ± 3 | 106 ± 5 | 104 ± 9 | 105 ± 5 | 101 ± 8 | 101 ± 11 | 97 ± 9 | 100 ± 31 | 112 ± 13 | 114 ± 14 | 104 ± 15 | 109 ± 11 | 98 ± 11 | |
PTT (seconds) | TEA | 89 ± 16 | 79 ± 15 | 85 ± 24 | 81 ± 27 | 86 ± 10 | 91 ± 26 | 93 ± 15 | 76 ± 4 | 92 ± 30 | 134 ± 22 | 103 ± 40 | 109 ± 22 | 79 ± 42 | 97 ± 48 | 107 ± 48 | 43 ± 25 |
Control | 84 ± 21 | 81 ± 18 | 86 ± 27 | 84 ± 27 | 82 ± 19 | 90 ± 30 | 75 ± 19 | 88 ± 19 | 98 ± 19 | 121 ± 25 | 111 ± 30 | 100 ± 33 | 87 ± 41 | 69 ± 17 | 79 ± 27 | 58 ± 14 | |
Creatinine (mg/dl) | TEA | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.2 | 0.8 ± 0.1 | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.4 | 1.0 ± 1.0 | 1.1 ± 1.3 | 1.2 ± 2.0 |
Control | 0.7 ± 0.1 | 0.8 ± 0.1 | 0.7 ± 0.1 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.3 | 0.8 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.2 | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.2 | 0.7 ± 0.1 | |
AST (U/L) | TEA | 38 ± 13 | 42 ± 22 | 38 ± 14 | 45 ± 18 | 48 ± 20 | 47 ± 19 | 51 ± 22 | 52 ± 18 | 60 ± 21 | 348 ± 220 | 116 ± 62 | 54 ± 25 | 40 ± 19 | 32 ± 15 | 30 ± 14 | 41 ± 48 |
Control | 34 ± 11 | 40 ± 12 | 40 ± 15 | 40 ± 13 | 43 ± 10 | 46 ± 13 | 51 ± 8 | 51 ± 13 | 58 ± 19 | 319 ± 116 | 86 ± 27 | 45 ± 12 | 33 ± 5 | 30 ± 4 | 29 ± 12 | 32 ± 9 | |
ALT (U/L) | TEA | 77 ± 15 | 80 ± 6 | 63 ± 13 | 77 ± 9 | 76 ± 5 | 70 ± 9 | 66 ± 4 | 63 ± 8 | 50 ± 8 | 111 ± 30 | 105 ± 25 | 93 ± 24 | 77 ± 24 | 74 ± 19 | 66 ± 16 | 49 ± 15 |
Control | 76 ± 13 | 70 ± 12 | 63 ± 11 | 62 ± 9 | 61 ± 11 | 55 ± 8 | 55 ± 9 | 47 ± 7 | 46 ± 10 | 115 ± 28 | 105 ± 21 | 88 ± 15 | 82 ± 9 | 81 ± 13 | 71 ± 13 | 50 ± 12 | |
Amylase (U/L) | TEA | 2155 ± 368 | 2606 ± 103 | 2388 ± 509 | 2808 ± 137 | 2960 ± 280 | 2895 ± 250 | 3011 ± 187 | 3045 ± 319 | 3153 ± 965 | 8726 ± 3736 | 8196 ± 4195 | 6745 ± 4591 | 4316 ± 2923 | 3966 ± 2930 | 3909 ± 3319 | 3225 ± 3886 |
Control | 1971 ± 432 | 2165 ± 476 | 2249 ± 814 | 2278 ± 556 | 2479 ± 541 | 2567 ± 699 | 2876 ± 953 | 2733 ± 978 | 3261 ± 1296 | 10186 ± 5195 | 9001 ± 6610 | 8472 ± 5937 | 8109 ± 7347 | 6726 ± 5501 | 10129 ± 6670 | 7926 ± 6196 | |
Bilirubin (mg/dl) | TEA | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.4 ± 0.2 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 |
Control | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.3 ± 0.1 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.2 ± 0.0 |