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Table 2 Clinical and demographic characteristics of the study cohort comparing patients with no AKI versus transient AKI versus intrinsic AKI

From: Urinary output and fractional excretion of sodium and urea as indicators of transient versus intrinsic acute kidney injury during early sepsis

 

No AKI (n = 28)

Transient AKI (n = 57)

Intrinsic AKI (n = 22)

P value

Gender male (%)

51.7

54.4

59.1

0.93

Age (years, mean/SD)

55.4 (17.3)

62.6 (13.3)

63.1 (14.9)

0.08

CKD on admission (MDRD <60 ml/min/1.73 m2) (%)

10.7

8.8

9.1

0.96

APACHE II score on the first day of admission

21 (10)

22 (8)

24.5 (9)

0.08

Positive fluid balance first 24 hours (mean/SD)

2.2 (1.8)

3.3 (1.9)

5.4 (2.7)

<0.001

Use of diuretics on the first day of admission (%)

7.1

19.3

27.3

0.16

RRT need during ICU stay (%)

0

1.8

59.1

<0.001

Vasopressor use (%)

32.1

61.4

86.4

<0.001

Total dose of noradrenaline first 24 hours (μg/kg/min)

0.13 (0.22)

0.12 (0.19)

0.16 (0.28)

0.65

Maximum dose of noradrenaline during first 24 hours (μg/kg/min)

0.28 (0.34)

0.32 (0.47)

0.49 (0.68)

0.66

Need for ventilation during ICU stay (%)

39.3

50.9

86.4

0.003

LOS (days)

5 (6)

5 (10)

38 (32)

0.014

ICU mortality (%)

21.4

15.8

54.2

0.002

Mortality at 90 days (%)

28.6

24.6

59.1

0.012