One size does not fit all in severe infection: obesity alters outcome, susceptibility, treatment, and inflammatory response

Table 3 Pattern of infection of patients with septic shock

	Actual body mass index category, kg/m²			P value
	BMI <25 (n = 276)	BMI 25 to <30 (n = 209)	BMI ≥30 (n = 245)
Primary source of infection, number (percentage)
Lung	137 (49.8)	94 (45)	85 (35)	0.003^a
Abdomen	69 (25.1)	54 (25.8)	73 (30)	0.41
Genitourinary	10 (3.6)	11 (5.3)	13 (5.3)	0.58
Blood	13 (4.7)	14 (6.7)	16 (6.6)	0.57
Skin	17 (6.2)	14 (6.7)	26 (10.7)	0.12
Other^b	23 (8.4)	21 (10)	25 (10.3)	0.72
Pathogen type in cultures, number (percentage)
Gram-positive	81 (29.5)	53 (25.4)	81 (33.3)	0.18
Gram-negative	68 (24.7)	52 (24.9)	46 (18.9)	0.21
Fungal	43 (15.6)	23 (11)	20 (8.2)	0.03^a

^aP <0.05. ^bBone/joint/central nervous system infection. P values were calculated for statistical difference between three patient groups with the use of chi-square test. BMI, body mass index.

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