| 4-factor PCC regimen |  | |
---|---|---|---|
 | 25 IU/kg (n = 29) | 40 IU/kg (n = 30) | P value |
Age, years | 77.7 ± 9.4 | 75.2 ± 11.1 | 0.265 |
Male gender | 19 (65.5) | 23 (76.7) | 0.344 |
Body weight, kg | 76.9 ± 17.6 | 76.7 ± 13.5 | 0.779 |
Medical history | Â | Â | NS |
   Hypertension | 18 (62.1) | 21 (70.0) |  |
   Atrial fibrillation | 18 (62.1) | 18 (60.0) |  |
   Previous ischemic stroke | 3 (10.3) | 4 (13.3) |  |
   Diabetes mellitus | 8 (27.6) | 7 (23.3) |  |
   Hypercholesterolemia | 3 (10.3) | 5 (16.7) |  |
Blood pressure, mm Hg | Â | Â | Â |
   SBP | 154 ± 23.4 | 162 ± 32.7 | 0.359 |
   DBP | 84.1 ± 14.0 | 86.2 ± 18.3 | 0.524 |
Blood glucose, mmol/L | 7.7 ± 3.1 | 7.6 ± 2.4 | 0.946 |
Onset to diagnosis, hrs | 29.4 ± 51.6 | 45.8 ± 82.0 | 0.213 |
INR | 2.9 ± 1.1 | 3.2 ± 1.9 | 0.660 |
GCS | 13.3 ± 2.7 | 13.2 ± 2.8 | 0.846 |
Type of intracranial haemorrhage | Â | Â | 0.862 |
   Intracerebral haemorrhage | 18 (64.3) | 18 (62.1) |  |
   Acute subdural haemorrhage | 10 (35.7) | 11 (37.9) |  |
Haematoma volume, cm 3 | 23.8 ± 18.5 | 16.5 ± 18.9 | 0.438 |