Lower short- and long-term mortality associated with overweight and obesity in a large cohort study of adult intensive care unit patients

Abhyankar, Swapna; Leishear, Kira; Callaghan, Fiona M; Demner-Fushman, Dina; McDonald, Clement J

doi:10.1186/cc11903

Critical Care

Table 5 Multivariable logistic regression results for 30-day and one-year mortality risk.

From: Lower short- and long-term mortality associated with overweight and obesity in a large cohort study of adult intensive care unit patients

	30 days Odds ratio (95% CI)	1 year Odds oatio (95% CI)
BMI category (ref, normal weight (18.5 to < 25 kg/m²))
Underweight (< 18.5 kg/m²)	1.41 (1.13, 1.76)^b	1.51 (1.18, 1.94)^b
Overweight (25 to < 30 kg/m²)	0.81 (0.70, 0.93)^b	0.68 (0.59, 0.79)^b
Obese (30 to < 40 kg/m²)	0.74 (0.64, 0.86)^b	0.57 (0.49, 0.67)^b
Age category (ref < 45 years)
45 to < 65 years	2.44 (1.93, 3.07)^b	2.56 (2.01, 3.28)^b
65 to < 80 years	3.91 (3.08, 4.96)^b	4.43 (3.43, 5.72)^b
80+ years	8.16 (6.39, 10.43)^b	7.51 (5.72, 9.85)^b
Female	0.91 (0.81, 1.02)	0.87 (0.77, 0.99)^b
Race (ref, White)
Black	0.60 (0.48, 0.75)^b	0.69 (0.55, 0.86)^b
Hispanic or Latino	0.53 (0.35, 0.81)^b	0.48 (0.31, 0.75)^b
Asian	0.46 (0.30, 0.69)^b	0.89 (0.61, 1.30)
Other	1.15 (0.82, 1.63)	1.21 (0.83, 1.76)
Insurance (ref, CMS)
Private	0.85 (0.74, 0.98)^b	0.83 (0.72, 0.95)^b
Other	0.91 (0.71, 1.17)	0.63 (0.46, 0.86)^b
Smoker	a	1.26 (1.11, 1.43)^b
Obesity-related conditions
Diabetes	0.82 (0.71, 0.94)^b	a
Coronary artery disease	0.68 (0.59, 0.78)^b	0.65 (0.56, 0.75)^b
Stroke	2.15 (1.84, 2.51)^b	1.44 (1.21, 1.73)^b
Hypertension	0.64 (0.56, 0.72)^b	0.58 (0.51, 0.66)^b
Other CVD	a	1.47 (1.27, 1.69)^b
Obesity-related cancer^c	1.38 (1.00, 1.92)	1.89 (1.36, 2.62)^b
Kidney disease	1.50 (1.32, 1.71)^b	1.94 (1.70, 2.21)^b
Osteoarthritis	0.28 (0.15, 0.54)^b	0.39 (0.23, 0.66)^b
Other relevant diagnoses
Sepsis	1.56 (1.32, 1.85)^b	1.51 (1.24, 1.82)^b
Pulmonary embolism	2.06 (1.47, 2.88)^b	a
ICU Unit (ref, MICU)
CCU	0.76 (0.63, 0.92)^b	0.62 (0.51, 0.74)^b
CSRU	0.15 (0.12, 0.19)^b	0.17 (0.13, 0.21)^b
SICU	0.66 (0.57, 0.77)^b	0.73 (0.62, 0.85)^b
SAPS^d	1.18 (1.16, 1.19)^b	1.09 (1.07, 1.10)^b
ICU interventions
Ventilation	1.36 (1.17, 1.59)^b	a
Transfusion	0.74 (0.65, 0.84)^b	1.18 (1.04, 1.34)^b
TPN	0.85 (0.68, 1.05)	a

^aDropped out of the final multivariable model. ^bP < 0.05. ^cObesity-related cancers: breast, colon, uterine, esophageal, pancreatic, ovarian, and kidney. ^dSAPS was calculated without the age component because age was an independent variable in the analysis.

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