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Table 2 Antibiotic distribution in the entire cohort and in patients with community-acquired and nosocomial sepsis

From: Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality

Antibiotics

Global

n= 1,372

Community-acquired

n= 1,022 (74.5%)

Nosocomial

n= 350 (25.5%)

P

β-lactams

902 (65.7%)

708 (69.3%)

194 (55.4%)

<0.001

Carbapenems

345 (25.1%)

218 (21.3%)

127 (36.3%)

<0.001

Quinolones

282 (20.6%)

241 (23.6%)

41 (11.7%)

<0.001

Aminoglycosides

183 (13.3%)

114 (11.2%)

69 (19.7%)

<0.001

Macrolides

60 (4.4%)

54 (5.3%)

6 (1.7%)

0.004

Anti-gram-positive

161 (11.7%)

96 (9.4%)

65 (18.6%)

<0.001

Antifungals

38 (2.8%)

20 (2.0%)

18 (5.1%)

0.004

Others

151 (11.0%)

111 (10.9%)

40 (11.4%)

0.767