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Table 2 Assessment of methodological quality and risk of bias in the included studies

From: Clinical review: Predictive value of neutrophil gelatinase-associated lipocalin for acute kidney injury in intensive care patients

Study

Prospective observational study design

Clearly described selection criteria

Validated diagnostic scale for AKI used

Clearly described NGAL measurements

Conflict of interests

Risk of bias

de Geus et al. [21]

Yes

Yes

Yes

Yes

Yes

Low

Endre et al. [22]

Yes

Yes

Yes

Yes

Yes

Low

Doi et al. [24]

Yes

Yes

Yes

Yes

No

Low

Cruz et al. [25]

Yes

Yes

Yes

Yes

No

Low

Constantin et al. [26]

Yes

Yes

Yes

Yes

?

Low

Mårtensson et al. [27]

No

Yes

Yes

Yes

?

Medium

Metzger et al. [28]

No

Yes

Yes

Yes

Yes

Medium

Siew et al. [29]

Yes

Yes

Yes

Yes

No

Low

Makris et al. [30]

Yes

Yes

Yes

Yes

?

Low

Kokkoris et al.a [31]

Yes

Yes

Yes

Yes

No

Low

Linko et al.b

Yes

Yes

N/A

Yes

No

Low

  1. aStudy published as abstract only; author contacted to obtain extracted data; bstudy unpublished. AKI, acute kidney injury; NGAL, neutrophil gelatinase-associated lipocalin.
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Critical Care

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