An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients

Table 1 Demographic and baseline characteristics of the patients

	Before ASP (n= 139)	After ASP (n= 130)	P value
Male	62 (45%)	67 (52%)	0.310
Older than 70 years	50 (36%)	42 (32%)	0.614
Medical admission	89 (64%)	90 (69%)	0.439
Transferred from external institution	44 (32%)	52 (40%)	0.194
APACHE II (mean ± SD)	21.9 ± 6.2	22.6 ± 5.2	0.318
Malignancy	42 (30%)	30 (23%)	0.237
Previous HSCT	2 (1%)	8 (6%)	0.085
Renal replacement therapy	13 (9%)	13 (10%)	0.858
Infectious Disease Service consultations	9 (7%)	22 (17%)	0.013
ICU mortality	26 (19%)	18 (13%)	0.362

Malignancy, active malignancy (cancer within in past 6 months, or currently receiving treatment such as radiation or chemotherapy) or malignancy within 10 years before admission; HSCT, hematopoietic stem cell transplant (defined as autologous or allogenic stem cell transplantation within the past 5 years and includes both myeloablative and nonmyeloablative transplant protocols); renal replacement therapy, all forms of dialysis (intermittent hemodialysis, continuous renal replacement therapy, and so on).

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