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Table 2 Patient characteristics of all patients and compared between survivors and non-survivors.

From: Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective FINNAKI study

 

Data

available

All

n= 296

Survivors

n= 180

Non-survivors

n= 116

P value

Age (years)

296

64 [55-73]

62 [50-69]

70 [58-77]

< 0.001

Male gender

296

197 (66.6)

121 (67.2)

76 (65.5)

0.801

Baseline weight (kg)

296

80 [70-95]

85 [70-100]

76 [69-87]

0.001

Baseline creatinine (umol/L)

202

86 [70-116]

91 [71-117]

81 [68-114]

0.201

Emergency admission

292

271 (92.8)

164 (92.7)

107 (93.0)

0.900

Surgical admission

295

94 (31.9)

59 (33.0)

35 (30.2)

0.701

SAPS II score

296

51 [40-65]

46 [36-56]

63 [51-77]

< 0.001

SAPS II score without age points

296

40 [29-55]

36 [25-45]

51 [37-64]

< 0.001

Severe sepsis (during ICU stay)

296

142 (48.0)

73 (40.6)

69 (59.5)

0.002

Vasoactives (during ICU stay)

296

251 (84.8)

143 (79.4)

108 (93.1)

0.001

Mechanical ventilation (during ICU stay)

296

220 (74.3)

117 (65.0)

103 (88.8)

< 0.001

Parameters at RRT initiation

     

SOFA score on RRT initiation day

290

10 [7-12]

9 [6-11]

12 [9-14]

< 0.001

Renal SOFA score on RRT initiation day

290

3 [2-3]

3 [1-4]

4 [2-4]

0.022

Cumulative balance on RRT initiation day (L)

283

3.8 [1.3-8.3]

3.1 [0.3-6.4]

6.2 [2.2-9.7]

< 0.001

Fluid accumulation on RRT initiation day (%)

283

5.1 [1.5-10.3]

3.6 [0.3-8.2]

8.0 [3.0-12.9]

< 0.001

Urine output mL/24 hr on RRT initiation day

278

325 [80-1191]

510 [157-1701]

150 [35-496]

< 0.001

Received diuretics prior to RRT initiation

296

202 (68.2)

117 (65.0)

85 (73.3)

0.160

Received colloids prior to RRT initiation

290

208 (71.7)

114 (64.4)

94 (83.2)

< 0.001

Amount of colloids received on ICU prior to RRT initiation (mL)

291

500 [0-1500]

500 [0-1250]

976 [138-2000]

0.001

Creatinine prior to RRT initiation (umol/L)

290

261 [168-427]

279 [169-506]

237 [164-336]

0.049

Lactate prior to RRT initiation (mmol/L)

276

2.4 [1.2-6.0]

1.8 [1.1-4.8]

3.8 [1.7-8.0]

< 0.001

pH prior to RRT initiation

291

7.29 [7.18-7.38]

7.31 [7.20-7.38]

7.25 [7.17-7.37]

0.072

Base excess prior to RRT initiation (mmol/L)

292

-8.8 [-13.6- -4.0]

-7.6 [-13.0- -3.4]

-10.0 [-13.9- -5.1]

0.046

Time from ICU admission to RRT initiation (hours)

290

14.0 [3.3-41.5]

10.9 [2.5-42.1]

19.2 [6.3-41.3]

0.039

CRRT as initial modality

296

215 (72.6)

121 (67.2)

94 (81.0)

0.011

Length of stay (days)

     

ICU

296

5.5 [2.2-10.9]

6.0 [2.8-11.6]

4.0 [1.8-9.9]

0.039

Hospital

294

14.5 [6.0-27.3]

20.0 [11.0-32.0]

6.0 [2.0-18.0]

< 0.001

  1. Continuous variables expressed as median [interquartile range]. Nominal variables expressed as number (%). ICU, intensive care unit; RRT, renal replacement therapy; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.
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