Investigating risk factors for psychological morbidity three months after intensive care: a prospective cohort study

Table 5 Final multiple regression models of strongest* risk factors for post-ICU PTSD at three months

	R² Cumulative variance	Clinical factors† (column 1)		Clinical and acute psychological factors (column 2)		Clinical, acute psychological and chronic psychological factors (column 3)
		Unstandardised coefficients (95% CI)	p	Unstandardised coefficients (95% CI)	p	Unstandardised coefficients (95% CI)	p
Duration of sedation - days		0.69 (0.12, 1.27)	<0.05	0.35 (-0.17, 0.87)	0.18	0.33 (-0.18, 0.84)	0.20
Benzodiazepines (yes/no)		3.98 (-1.01, 8.97)	0.12	1.26 (-3.22, 5.73)	0.58	0.352 (-4.01,4.72)	0.87
Antipsychotics (yes/no)		3.32 (-1.61, 8.24)	0.18	1.88 (-2.47, 6.24)	0.39	1.06 (-3.18, 5.29)	0.62
	0.18 (18%)
ICU Mood				0.31 (0.14, 0.47)	<0.01	0.25 (0.09, 0.42)	<0.01
BIPQ (timeline)				0.79 (0.05, 1.52)	<0.05	0.71 (-0.003, 1.43)	0.05
Intrusions (yes/no)				5.21 (0.91, 9.51)	<0.05	5.83 (1.65, 10.02)	<0.01
	0.39 (39%)
Psychological history (yes/no)						6.55 (0.99, 12.10)	<0.05
Alcohol use (yes/no)						4.63 (-1.51, 10.77)	0.14
	0.45 (45%)

PTSD scores range from 0 to 51 on the post-traumatic stress diagnostic scale (PDS).
* Strongest risk factors were identified in a previous univariable analysis and separate multivariable analyses of each group of risk factors (clinical, acute psychological, chronic health)
† Factors were entered in this final multiple regression in the following order: 1. Clinical, 2. acute psychological, 3. chronic psychological. There are no socio-demographic factors or chronic physical conditions in this table as neither S-D factors nor chronic physical conditions had significant associations with PTSD in the univariable analysis.
BIPQ, Brief Illness Perception Questionnaire

ISSN: 1364-8535