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Table 1 Characteristics of the individuals included in the study

From: A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia

 

H1N1 influenza A

Bacterial pneumonia

SIRS

Mixed influenza A/bacterial pneumonia

Healthy control

Demographics

     

Number in group

8

16

12

3

18

Age (years)

34 ± 12

62 ± 13

61 ± 16

39 ± 13

43 ± 16

Male/Female

3/5

7/9

10/2

1/2

6/12

Comorbidities (%)

     

Hypertension

12.5

31.3

58.3

0

16.6

Heart disease

0

37.5

33.3

33.3

0

Diabetes

12.5

12.5

25.0

0

0

COPD

25

37.5

16.7

0

0

Cancer

0

12.5

0

0

0

Trauma

0

0

8.3

0

0

Recent surgery (last 7 days)

0

6.25

33.3

33.3

0

Severity of disease

     

Mortality (%)

0

31.3

0

0

NA

APACHE II

15 ± 3.8

18 ± 6.6

16 ± 4.5

18 ± 5.6

NA

Treatment (%)

     

Mechanical ventilation

100

93.8

75

100

NA

Renal dialysis

12.5

6.3

8.3

33.3

NA

Vasopressor therapy

62.5

56.3

16.7

66.6

NA

  1. APACHE II, Acute Physiology And Chronic Health Evaluation score [11]; COPD, chronic obstructive pulmonary disease; SIRS, systemic inflammatory response syndrome. Plus-minus values are median ± standard deviation.