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Figure 3 | Critical Care

Figure 3

From: Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

Figure 3

Urinary biomarkers of renal injury. ( A ) Kidney injury molecule-1 (KIM-1); (B) neutrophil gelatinase-associated lipocalin (NGAL); ( C ) glutathione S-transferase A1-1 (GSTA1-1); ( D ) GSTP1-1; and ( E ) IL-18 levels in urine; measured at various times points for placebo and alkaline phosphatase treatment during the first seven days. Urinary excretion of KIM-1 and IL-18 was lower in AP-treated patients relative to placebo-treated patients. Data are expressed as mean ± SEM (one-side depicted) and analyzed by ANOVA with repeated measurements over the complete curve with baseline as covariate.

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Critical Care

ISSN: 1364-8535