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Table 7 Multivariate logistic regression analysis of mortality related to multiple prognostic factors; (N = 323)

From: The microbiological profile and presence of bloodstream infection influence mortality rates in necrotizing fasciitis

Variables

OR (95% CI)1

P-value2

Age, years

0.99 (0.97 to 1.02)

0.607

Gender, males (%)

1.16 (0.50 to 2.67)

0.731

Pre-existing disease

  

   Hypotension

5.68 (2.21 to 14.59)

<0.001*

   Heart disease

2.89 (1.09 to 7.62)

0.033*

   Liver disease

2.54 (1.10 to 5.87)

0.029*

Clinical features

  

   Operation within 24 hours

0.59 (0.27 to 1.29)

0.182

   Debridement > = 3 times

0.19 (0.08 to 0.43)

<.001*

Gram negative organism in wound culture

  

   Vibrio spp.

5.60 (1.82 to 17.25)

0.003*

Fungus in wound culture

0.52 (0.04 to 7.54)

0.632

Gram positive organism in blood culture

  

   Streptococcus group A

15.93 (1.95 to 130.34)

0.010*

Gram negative organism in blood culture

  

   Aeromonas spp.

3.50 (0.46 to 26.76)

0.227

   Vibrio spp.

1.19 (0.29 to 4.92)

0.806

  1. 1 Odds ratio with 95% confidence interval (OR: (95% CI) were derived through multivariate logistic regression model.
  2. 2 P-values from multivariate logistic regression analysis, were used to identify the significance of respective OR.*P <0.05.