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Table 4 Association of mortality with microbiologic characteristics of 279 patients with positive growth of wound cultures

From: The microbiological profile and presence of bloodstream infection influence mortality rates in necrotizing fasciitis

Variable

Survival

(n= 232)

Death

(n= 47)

P-value

Gram-positive cocci

   

Aerobic

   

   Staphylococcus aureus

   

Methicillin-susceptible S. aureus

39 (16.8)

3 (6.4)

0.075

Methicillin-resistant S. aureus

47 (20.3)

7 (14.9)

0.543

   Coagulase-negative Staphylococcus

12 (5.2)

1 (2.1)

0.703

   Streptococcus

   

Beta-hemolytic (Group A)

32 (13.8)

5 (10.6)

0.645

Beta-hemolytic (Group B)

4 (1.7)

2 (4.3)

0.267

Non-group A or B

   

S. viridans

33 (14.2)

5 (10.6)

0.644

   Enterococcus faecalis

37 (15.9)

9 (19.1)

0.666

Anaerobic

   

   Peptostreptococcus

30 (12.9)

8 (17.0)

0.485

Gram-positive rods

   

Aerobic

   

   Corynebacterium

7 (3.0)

1 (2.1)

1.000

Anaerobic

   

   Clostridium spp.

2 (0.9)

3 (6.4)

0.035*

Gram negative rods

   

Aerobic

   

   Acinetobacter baumannii

20 (8.6)

3 (6.4)

0.776

   Aeromonas spp.

18 (7.8)

4 (8.5)

0.773

   Citrobacter spp.

10 (4.3)

1 (2.1)

0.697

   E.coli.

29 (12.5)

8 (17.0)

0.478

   Enterobacter spp.

15 (6.5)

5 (10.6)

0.349

   Klebsiella pneumoniae

36 (15.5)

5 (10.6)

0.501

   Pseudomonas aeruginosa

16 (6.9)

3 (6.4)

1.000

   Vibrio spp.

11 (4.7)

11 (23.4)

<.001*

   Eikenella corrodens

4 (1.7)

-

-

   Klebsiella oxytoca

3 (1.3)

-

-

   Proteus mirabillis

23 (9.9)

-

-

   Serratia marcescens

7 (3.0)

-

-

   Other gram negative rods

12 (5.2)

3 (6.4)

0.724

Anaerobic

   

   Prevotella spp.

12 (5.2)

-

-

   Bacteroides fragilis

11 (4.7)

4 (8.5)

0.292

   Fusobacterium

1 (0.4)

-

-

   Veillonella

2 (0.9)

1 (2.1)

0.426

Fungus

5 (2.2)

1 (2.1)

1.000

  1. Data were summarized as n (%) for subjects with positive growth of wound culture. Subjects were classified into "Death" and Survival" categories. * P <0.05 denotes a significant difference between the Death, and Survival groups. P-values were derived through Fisher's exact test.