Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model

Table 1 Experimental design of the study

	Time(s) of infection	Bacterial and yeast delivery (CFU/mouse)	Caspofungin treatment	Day(s) of sacrifice
Ctr	/	Saline solution	none	Day 2, Day 4
Ca	T0	1 × 10⁵ C. albicans	none	Day 2, Day 4
Pa	Day 2	1 × 10⁷ P. aeruginosa	none	Day 4
CaPa	T0, Day 2	T0: 1 × 10⁵ C. albicans d2: 1 × 10⁷ P. aeruginosa	none	Day 4
CaPaCasp0	T0, Day 2	T0: 1 × 10⁵ C. albicans d2: 1 × 10⁷ P. aeruginosa	T0 to Day 4	Day 4
CaPaCasp1	T0, Day 2	T0: 1 × 10⁵ C. albicans d2: 1 × 10⁷ P. aeruginosa	Day 1 to 4	Day 4

ISSN: 1364-8535