Table 3 Discriminative power of mean arterial pressure to predict acute kidney insufficiency at H72
AUC for MAP averaged over H6 to H24 | Best MAP threshold (mmHg) | Sensitivity | Specificity | AUC for MAP averaged over H12 to H24 | Best MAP threshold (mmHg) | Sensitivity | Specificity | |
|---|---|---|---|---|---|---|---|---|
Patients with no AKI at H6 (n = 116) | 0.53 (0.43 to 0.62) | - | - | - | 0.50 (0.41 to 0.60) | - | - | - |
Patients with AKI at H6 (n = 101) | 0.74* (0.66 to 0.83) | 69 | 0.53 (0.38 to 0.69) | 0.91 (0.81 to 0.97) | 0.75** (0.66 to 0.84) | 70 | 0.59 (0.42 to 0.74) | 0.86 (0.75 to 0.94) |
Patients with non septic shock (n = 90) | 0.60 (0.49 to 0.11) | - | - | - | 0.59 (0.48 to 0.59) | - | - | - |
Septic shock patients (n = 127) | 0.72 (0.63 to 0.79) | 72 | 0.56 (0.38 to 0.72) | 0.84 (0.74 to 0.91) | 0.72 (0.63 to 0.80) | 72 | 0.61 (0.42 to 0.77) | 0.84 (0.74 to 0.91) |
Non septic shock patients only: | ||||||||
Patients with no AKI at H6 (n = 52) | 0.57 (0.42 to 0.71) | - | - | - | 0.47 (0.33 to 0.61) | - | - | - |
Patients with AKI at H6 (n = 38) | 0.59 (0.42 to 0.74) | - | - | - | 0.61 (0.44 to 0.77) | - | - | - |
Septic shock patients only: | ||||||||
Patients with no AKI at H6 (n = 63) | 0.52 (0.39 to 0.64) | - | - | - | 0.53 (0.40 to 0.66) | - | - | - |
Patients with AKI at H6 (n = 64) | 0.83†,†† (0.72 to 0.92) | 72 | 0.72 (0.51 to 0.88) | 0.87 (0.72 to 0.96) | 0.84‡,‡‡ (0.72 to 0.92) | 72 | 0.78 (0.56 to 0.93) | 0.89 (0.72-0.96) |