| 1 hour | 3 hours | 6 hours | 24 hours | ||||
---|---|---|---|---|---|---|---|---|
 | PHARLAP | Control | PHARLAP | Control | PHARLAP | Control | PHARLAP | Control |
VT, mls | 519 ± 56 | 501 ± 30 | 517 ± 51 | 529 ± 58 | 529 ± 56 | 542 ± 49 | 463 ± 42 | 563 ± 65 |
RR, bpm | 21 ± 2 | 21 ± 1 | 20 ± 2 | 21 ± 2 | 21 ± 2 | 21 ± 2 | 22 ± 2 | 20 ± 2 |
FIO2 | 0.47 ± 0.03 | 0.59 ± 0.04 | 0.5 ± 0.04 | 0.5 ± 0.03 | 0.4 ± 0.05 | 0.57 ± 0.05 | 0.4 ± 0.04 | 0.5 ± 0.04 |
PEEP, cm H2O | 17.4 ± 1 | 11.6 ± 1 | 17.4 ± 1* | 11 ± 0.5 | 16.7 ± 1* | 10 ± 0.6 | 15 ± 1* | 10 ± 0.5 |
Pplateau, cm H2O | 28.9 ± 1.2 | 27.1 ± 1.2 | 28.3 ± 1.1 | 26.6 ± 1.1 | 29 ± 0.8 | 26 ± 0.8 | 27.6 ± 1.5 | 26.9 ± 1.4 |
Arterial pH | 7.34 ± 0.02 | 7.36 ± 0.02 | 7.34 ± 0.02 | 7.34 ± 0.03 | 7.34 ± 0.02 | 7.36 ± 0.01 | 7.36 ± 0.01 | 7.35 ± 0.01 |
PaCO2, mm Hg | 49 ± 5 | 46 ± 5 | 47 ± 4 | 48 ± 6 | 48 ± 3 | 45 ± 3 | 45 ± 3 | 46 ± 3 |