Table 4 Key points regarding gene-based therapies for ALI/ARDS
From: Clinical Review: Gene-based therapies for ALI/ARDS: where are we now?
ALI/ARDS may be amenable to gene-based therapies |
Ongoing advances in our understanding of the pathophysiology of ALI/ARDS have revealed multiple therapeutic targets for gene-based approaches |
Numerous gene-based approaches have demonstrated promise in relevant preclinical models |
The clinical potential for gene-based approaches to ALI/ARDS remains to be realized |
Multiple barriers exist to successful gene-based approaches for ALI/ARDS |
A greater understanding of the molecular mechanisms underlying injury and repair in |
ALI/ARDS, coupled with improvements in gene-based approaches, offer hope for ALI/ARDS |