Table 2 TLR4/TLR2 polymorphisms and time course of perioperative cytomine serum concentrations
| Â | Â | Sample times | ||
|---|---|---|---|---|
| Â | Â | A | B | C |
IL-1β (pg/ml) | non-carrier | 8.2 (3.5 to 12.8) | 14.4 (9.3 to 19.4) | 9.9 (4.8 to 15.0) |
| Â | TLR4 SNP | 6.7 (-4.1 to 17.5) | 12.3 (1.2 to 23.5) | 11.5 (0.3 to 22.7) |
| Â | TLR2 SNP | 1.2 (-20.2 to 22.6) | 29.3 (6.0 to 52.6) | 12.4 (-12.0 to 36.9) |
IL-2 (pg/ml) | non-carrier | 2.6 (1.3 to 3.9) | 3.0 (1.7 to 4.4) | 2.4 (1.0 to 3.8) |
| Â | TLR4 SNP | 2.0 (-1.0 to 5.0) | 2.8 (-0.2 to 5.9) | 3.3 (0.2 to 6.4) |
| Â | TLR2 SNP | 1.1 (-4.8 to 7.0) | 1.8 (-4.6 to 8.2) | 1.0 (-5.7 to 7.8) |
IL-4 (pg/ml) | non-carrier | 4.9 (2.7 to 7.1) | 4.6 (2.2 to 7.0) | 4.2 (1.8 to 6.6) |
| Â | TLR4 SNP | 1.7 (-3.5 to 6.8) | 2.0 (-3.3 to 7.3) | 1.8 (-3.6 to 7.2) |
| Â | TLR2 SNP | 4.5 (-5.7 to 14.7) | 2.4 (-8.7 to 13.5) | 3.1 (-8.6 to 14.7) |
IL-5 (pg/ml) | non-carrier | 1.5 (0.7 to 2.4) | 2.6 (1.7 to 3.6) | 1.5 (0.6 to 2.5) |
| Â | TLR4 SNP | 0.9 (-1.1 to 2.9) | 1.4 (-0.7 to 3.5) | 0.7 (-1.4 to 2.9) |
| Â | TLR2 SNP | 1.1 (-3.0 to 5.1) | 1.4 (-3.0 to 5.8) | 0.8 (-3.8 to 5.36) |
IL-6 (pg/ml) | non-carrier | 18.8 (-48.4 to 86.0) | 554.1 (481.7 to 626.4)a | 350.4 (277.1 to 423.7)ab |
| Â | TLR4 SNP | 24.0 (-131.6 to 179.7) | 422.5 (262.1 to 583.0)a | 344.7 (182.6 to 506.9)a |
| Â | TLR2 SNP | 14.3 (-294.0 to 322.7) | 696.3 (361.1 to 1031.5)a | 405.7 (54.1 to 757.2) |
TNF-α (pg/ml) | non-carrier | 4.9 (-7.6 to 17.4) | 12.9 (-0.6 to 26.3) | 8.7 (-4.9 to 22.3) |
| Â | TLR4 SNP | 0.3 (-28.5 to 29.2) | 1.9 (-27.8 to 31.7) | 1.0 (-29.1 to 31.1) |
| Â | TLR2 SNP | 0.3 (-56.9 to 57.5) | 3.4 (-58.8 to 65.5) | 1.5 (-63.7 to 66.7) |