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Page 5 of 324

  1. Content type: Research

    Procalcitonin (PCT) testing can help in safely reducing antibiotic treatment duration in intensive care patients with sepsis. However, the cost-effectiveness of such PCT guidance is not yet known.

    Authors: Michelle M. A. Kip, Jos A. van Oers, Arezoo Shajiei, Albertus Beishuizen, A. M. Sofie Berghuis, Armand R. Girbes, Evelien de Jong, Dylan W. de Lange, Maarten W. N. Nijsten, Maarten J. IJzerman, Hendrik Koffijberg and Ron Kusters

    Citation: Critical Care 2018 22:293

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  2. Content type: Research

    Community-acquired pneumonia (CAP) remains a major cause of death worldwide. Mechanisms underlying the detrimental outcome despite adequate antibiotic therapy and comorbidity management are still not fully und...

    Authors: Sarah Berger, Cengiz Goekeri, Shishir K. Gupta, Julio Vera, Kristina Dietert, Ulrike Behrendt, Jasmin Lienau, Sandra-Maria Wienhold, Achim D. Gruber, Norbert Suttorp, Martin Witzenrath and Geraldine Nouailles

    Citation: Critical Care 2018 22:287

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  3. Content type: Research

    Acute respiratory failure occurs frequently in hospitalized patients and often starts before ICU admission. A risk stratification tool to predict mortality and risk for mechanical ventilation (MV) may allow fo...

    Authors: Mikhail A Dziadzko, Paul J Novotny, Jeff Sloan, Ognjen Gajic, Vitaly Herasevich, Parsa Mirhaji, Yiyuan Wu and Michelle Ng Gong

    Citation: Critical Care 2018 22:286

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  4. Content type: Research

    Given the pathophysiological key role of the host response to an infection rather than the infection per se, an ideal therapeutic strategy would also target this response. This study was designed to demonstrat...

    Authors: Hannah Knaup, Klaus Stahl, Bernhard M. W. Schmidt, Temitayo O. Idowu, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Jan T. Kielstein, Marius M. Hoeper and Sascha David

    Citation: Critical Care 2018 22:285

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    The Editorial to this article has been published in Critical Care 2018 22:357

  5. Content type: Research

    Intensive care unit (ICU) outcome prediction models, such as Acute Physiology And Chronic Health Evaluation (APACHE), were designed in general critical care populations and their use in obstetric populations i...

    Authors: Beth A. Payne, Helen Ryan, Jeffrey Bone, Laura A. Magee, Alice B. Aarvold, J. Mark Ansermino, Zulfiqar A. Bhutta, Mary Bowen, J. Guilherme Cecatti, Cynthia Chazotte, Tim Crozier, Anne-Cornélie J. M. de Pont, Oktay Demirkiran, Tao Duan, Marlot Kallen, Wessel Ganzevoort…

    Citation: Critical Care 2018 22:278

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  6. Content type: Research

    Whether perioperative hyperchloremia can induce postoperative acute kidney injury (AKI) is controversial. We investigated the association between perioperative hyperchloremia and postoperative AKI in patients ...

    Authors: Tak Kyu Oh, In-Ae Song, Se Joong Kim, Sung Yoon Lim, Sang-Hwan Do, Jung-Won Hwang, Jinhee Kim and Young-Tae Jeon

    Citation: Critical Care 2018 22:277

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    The Letter to this article has been published in Critical Care 2019 23:10

  7. Content type: Viewpoint

    Critical illness results in millions of deaths each year. Care for those with critical illness is often neglected due to a lack of prioritisation, co-ordination, and coverage of timely identification and basic...

    Authors: Carl Otto Schell, Martin Gerdin Wärnberg, Anna Hvarfner, Andreas Höög, Ulrika Baker, Markus Castegren and Tim Baker

    Citation: Critical Care 2018 22:284

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  8. Content type: Review

    The combination of thiamine, ascorbic acid, and hydrocortisone has recently emerged as a potential adjunctive therapy to antibiotics, infectious source control, and supportive care for patients with sepsis and...

    Authors: Ari Moskowitz, Lars W. Andersen, David T. Huang, Katherine M. Berg, Anne V. Grossestreuer, Paul E. Marik, Robert L. Sherwin, Peter C. Hou, Lance B. Becker, Michael N. Cocchi, Pratik Doshi, Jonathan Gong, Ayan Sen and Michael W. Donnino

    Citation: Critical Care 2018 22:283

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  9. Content type: Research

    Antibiotic exposure alters the microbiota, which can impact the inflammatory immune responses. Critically ill patients frequently receive antibiotic treatment and are often subjected to mechanical ventilation,...

    Authors: Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Achim D Gruber, Markus M Heimesaat, Jasmin Lienau, Fabian Schumacher, Burkhard Kleuser, Bastian Opitz, Norbert Suttorp, Martin Witzenrath and Holger C Müller-Redetzky

    Citation: Critical Care 2018 22:282

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  10. Content type: Research

    Metabolic alkalosis is common in patients with respiratory failure and may delay weaning in mechanically ventilated patients. Carbonic anhydrase inhibitors block renal bicarbonate reabsorption, and thus revers...

    Authors: Bassem Y Tanios, Maryam O Omran, Carlos Noujeim, Tamara Lotfi, Samir S Mallat, Pierre K Bou-Khalil, Elie A Akl and Houssam S Itani

    Citation: Critical Care 2018 22:275

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    The Letter to this article has been published in Critical Care 2019 23:138

  11. Content type: Research

    Sepsis is a life-threatening medical emergency requiring early diagnosis and urgent treatment. Knowledge is crucial, especially in major risk groups such as the elderly. We therefore assessed sophisticated kno...

    Authors: Sarah Eitze, Carolin Fleischmann-Struzek, Cornelia Betsch and Konrad Reinhart

    Citation: Critical Care 2018 22:273

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  12. Content type: Research

    Pathogenic enteric bacteria aspirated from the oropharynx are the main cause of ventilator-associated pneumonia (VAP). Using chlorhexidine (CHX) orally or selective decontamination has been shown to reduce VAP...

    Authors: Bengt Klarin, Anne Adolfsson, Anders Torstensson and Anders Larsson

    Citation: Critical Care 2018 22:272

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  13. Content type: Research

    Extracorporeal membrane oxygenation (ECMO) is a cardiorespiratory support technique for patients with circulatory or pulmonary failure. Frequently, large-volume fluid resuscitation is needed to ensure sufficie...

    Authors: Hyoungnae Kim, Jin Hyuk Paek, Joo Han Song, Hajeong Lee, Jong Hyun Jhee, Seohyun Park, Hae-Ryong Yun, Youn Kyung Kee, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Sejoong Kim and Jung Tak Park

    Citation: Critical Care 2018 22:270

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  14. Content type: Research

    Sepsis and related multiple organ dysfunction result in high morbidity and mortality. Angiotensin (Ang)-(1–7), a biologically active peptide, has various opposing effects of Ang II. Because the effect of Ang-(...

    Authors: Hsin-Jung Tsai, Mei-Hui Liao, Chih-Chin Shih, Shuk-Man Ka, Cheng-Ming Tsao and Chin-Chen Wu

    Citation: Critical Care 2018 22:269

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  15. Content type: Research

    Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The...

    Authors: Andrew J. Boyle, Fabiana Madotto, John G. Laffey, Giacomo Bellani, Tài Pham, Antonio Pesenti, B. Taylor Thompson, Cecilia M. O’Kane, Adam M. Deane and Daniel F. McAuley

    Citation: Critical Care 2018 22:268

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  16. Content type: Review

    Acute respiratory distress syndrome (ARDS) and hospital-acquired pneumonia (HAP) are major problems of public health in intensive care units (ICUs), occurring in 15% of critically ill patients. Among the facto...

    Authors: Nathalie De Freitas Caires, Alexandre Gaudet, Lucie Portier, Anne Tsicopoulos, Daniel Mathieu and Philippe Lassalle

    Citation: Critical Care 2018 22:280

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  17. Content type: Research

    Recent randomized trials have not found that polymyxin B hemoperfusion (PMX-HP) improves outcomes for patients with sepsis. However, it remains unclear whether the therapy could provide benefit for highly sele...

    Authors: Nattachai Srisawat, Somkanya Tungsanga, Nuttha Lumlertgul, Chalermchai Komaenthammasophon, Sadudee Peerapornratana, Nicha Thamrongsat, Khajohn Tiranathanagul, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Kriang Tungsanga and John A. Kellum

    Citation: Critical Care 2018 22:279

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  18. Content type: Research

    The continuous administration of opioids in critical care patients is a common therapy for the tolerance of mechanical ventilation. Opioid choice has a crucial impact on the length of mechanical ventilation. O...

    Authors: Daniel A Klaus, Albert M de Bettignies, Rudolf Seemann, Claus G Krenn and Georg A Roth

    Citation: Critical Care 2018 22:267

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  19. Content type: Research

    Central line-associated bloodstream infections (CLABSIs) are associated with increased mortality, hospital length of stay, and cost. Antimicrobial treatment guidelines for CLABSIs are primarily based on expert...

    Authors: Luis E Huerta, George E Nelson, Thomas G Stewart and Todd W Rice

    Citation: Critical Care 2018 22:266

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    The Editorial to this article has been published in Critical Care 2018 22:303

  20. Content type: Review

    Acute respiratory distress syndrome (ARDS) is a clinical entity that acutely affects the lung parenchyma, and is characterized by diffuse alveolar damage and increased pulmonary vascular permeability. Currentl...

    Authors: M Consuelo Bachmann, Caio Morais, Guillermo Bugedo, Alejandro Bruhn, Arturo Morales, João B Borges, Eduardo Costa and Jaime Retamal

    Citation: Critical Care 2018 22:263

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  21. Content type: Review

    Sepsis is one of the leading causes of morbidity and mortality worldwide. It is characterized by a dysregulated immune response to infections that results in life-threatening organ dysfunction and even death. ...

    Authors: Ghada Ankawi, Mauro Neri, Jingxiao Zhang, Andrea Breglia, Zaccaria Ricci and Claudio Ronco

    Citation: Critical Care 2018 22:262

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    The Letter to this article has been published in Critical Care 2019 23:14

  22. Content type: Letter

    Subsequent bloodstream infections (sBSI) occur with a delay after removal of the intravascular catheter (IVC) whose tip revealed microbial growth. Here we describe the epidemiology of sBSI in the intensive car...

    Authors: Niccolò Buetti, Elia Lo Priore, Rami Sommerstein, Andrew Atkinson, Andreas Kronenberg and Jonas Marschall

    Citation: Critical Care 2018 22:259

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  23. Content type: Review

    Measurement of arterial pressure is one of the most basic elements of patient management. Arterial pressure is determined by the volume ejected by the heart into the arteries, the elastance of the walls of the...

    Authors: S. Magder

    Citation: Critical Care 2018 22:257

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  24. Content type: Research

    Research on acute kidney injury (AKI) has focused on identifying early biomarkers. However, whether AKI could be diagnosed in the absence of the classic signs of clinical AKI and whether the condition of subcl...

    Authors: Fang Fang, Xiaohan Hu, Xiaomei Dai, Sanfeng Wang, Zhenjiang Bai, Jiao Chen, Jian Pan, Xiaozhong Li, Jian Wang and Yanhong Li

    Citation: Critical Care 2018 22:256

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  25. Content type: Research

    Despite aggressive application of continuous renal replacement therapy (CRRT) in critically ill patients with acute kidney injury (AKI), there is no consensus on diuretic therapy when discontinuation of CRRT i...

    Authors: Junseok Jeon, Do Hee Kim, Song In Baeg, Eun Jeong Lee, Chi Ryang Chung, Kyeongman Jeon, Jung Eun Lee, Wooseong Huh, Gee Young Suh, Yoon-Goo Kim, Dae Joong Kim, Ha Young Oh and Hye Ryoun Jang

    Citation: Critical Care 2018 22:255

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  26. Content type: Research

    Acute-on-chronic liver failure (ACLF) is a severe complication of cirrhosis and is defined by organ failure and high rates of short-term mortality. Patients with ACLF are managed with multiorgan support in the...

    Authors: Cornelius Engelmann, Karen Louise Thomsen, Nekisa Zakeri, Mohammed Sheikh, Banwari Agarwal, Rajiv Jalan and Rajeshwar P. Mookerjee

    Citation: Critical Care 2018 22:254

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  27. Content type: Research

    This study investigated changes in plasma level of soluble endothelial protein C receptor (sEPCR) in association with outcome in patients with septic shock. We explored sEPCR for early sepsis prognosis assessm...

    Authors: Agnès Chapelet, Yohann Foucher, Nathalie Gérard, Christophe Rousseau, Olivier Zambon, Cédric Bretonnière, Jean-Paul Mira, Béatrice Charreau and Christophe Guitton

    Citation: Critical Care 2018 22:251

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  28. Content type: Research

    High noise levels in the intensive care unit (ICU) are a well-known problem. Little is known about the effect of noise on sleep quality in ICU patients. The study aim is to determine the effect of noise on sub...

    Authors: Koen S. Simons, Eva Verweij, Paul M. C. Lemmens, Sam Jelfs, Munhum Park, Peter E. Spronk, Johannes P. C. Sonneveld, Hilde-Marieken Feijen, Marijke S. van der Steen, Armin G. Kohlrausch, Mark van den Boogaard and Cornelis P. C. de Jager

    Citation: Critical Care 2018 22:250

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  29. Content type: Research

    Ischemic stroke causes brain inflammation, which we postulate may result in lung damage. Several studies have focused on stroke-induced immunosuppression and lung infection; however, the possibility that strok...

    Authors: Cynthia S. Samary, Alane B. Ramos, Lígia A. Maia, Nazareth N. Rocha, Cíntia L. Santos, Raquel F. Magalhães, Amanda L. Clevelario, Pedro M. Pimentel-Coelho, Rosália Mendez-Otero, Fernanda F. Cruz, Vera L. Capelozzi, Tatiana P. T. Ferreira, Thea Koch, Marcelo Gama de Abreu, Claudia C. dos Santos, Paolo Pelosi…

    Citation: Critical Care 2018 22:249

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  30. Content type: Research

    Percutaneous tracheostomy (PT) is a common procedure in critical care medicine. No definite clinical practice guidelines recommended on the choice of the direction of skin incision, vertical or transverse for ...

    Authors: Sung Yoon Lim, Won Gun Kwack, Youlim Kim, Yeon Joo Lee, Jong Sun Park, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee and Young-Jae Cho

    Citation: Critical Care 2018 22:246

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  31. Content type: Research

    The use of in vivo videomicroscopy at the bedside has demonstrated microcirculatory flow disturbances in sepsis. The ability of in vivo videomicroscopy to detect changes in the prevalence of rolling and adhere...

    Authors: Bjorn K. Fabian-Jessing, Michael J. Massey, Michael R. Filbin, Peter C. Hou, Henry E. Wang, Hans Kirkegaard, Donald M. Yealy, William C. Aird, John A. Kellum, Derek C. Angus and Nathan I. Shapiro

    Citation: Critical Care 2018 22:240

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  32. Content type: Viewpoint

    Nutritional support continues to receive much attention as a possible intervention to prevent loss of lean tissue mass, promote recovery and re-establish proper immune function in critical care patients. Yet t...

    Authors: Gustav van Niekerk, Tanja Davis, Willem de Villiers and Anna-Mart Engelbrecht

    Citation: Critical Care 2018 22:231

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