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  1. The coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic. Preparing intensive care units (ICU) is an integral part of any pandemic response. In this review, we discuss the key prin...

    Authors: Ken Junyang Goh, Jolin Wong, Jong-Chie Claudia Tien, Shin Yi Ng, Sewa Duu Wen, Ghee Chee Phua and Carrie Kah-Lai Leong

    Citation: Critical Care 2020 24:215

    Content type: Review

    Published on:

    The Letter to this article has been published in Critical Care 2020 24:388

  2. Predicting successful liberation from mechanical ventilation (MV) in critically ill patients is challenging. Brain natriuretic peptide (BNP) has been proposed to help guide decision-making for readiness to lib...

    Authors: Jean Deschamps, Sarah K. Andersen, Jordan Webber, Robin Featherstone, Meghan Sebastianski, Ben Vandermeer, Janek Senaratne and Sean M. Bagshaw

    Citation: Critical Care 2020 24:213

    Content type: Research

    Published on:

    The Letter to this article has been published in Critical Care 2020 24:403

  3. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving technology that provides transient respiratory and circulatory support for patients with profound cardiogenic shock or refractory ca...

    Authors: Aurélien Roumy, Lucas Liaudet, Marco Rusca, Carlo Marcucci and Matthias Kirsch

    Citation: Critical Care 2020 24:212

    Content type: Review

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  4. Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presently become a rapidly spreading and devastating global pandemic. Veno-venous extracorporeal membrane oxygenation (V-V ECMO) ...

    Authors: Mariusz Kowalewski, Dario Fina, Artur Słomka, Giuseppe Maria Raffa, Gennaro Martucci, Valeria Lo Coco, Maria Elena De Piero, Marco Ranucci, Piotr Suwalski and Roberto Lorusso

    Citation: Critical Care 2020 24:205

    Content type: Review

    Published on:

  5. Citation: Critical Care 2020 24:204

    Content type: Letter

    Published on:

    The original article was published in Critical Care 2019 23:62

  6. The role of site of infection in sepsis has been poorly characterized. Additionally, sepsis epidemiology has evolved. Early mortality has decreased, but many survivors now progress into chronic critical illnes...

    Authors: Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge and Frederick A. Moore

    Citation: Critical Care 2020 24:203

    Content type: Research

    Published on:

  7. The use of the furosemide stress test (FST) as an acute kidney injury (AKI) severity marker has been described in several trials. However, the diagnostic performance of the FST in predicting AKI progression ha...

    Authors: Jia-Jin Chen, Chih-Hsiang Chang, Yen-Ta Huang and George Kuo

    Citation: Critical Care 2020 24:202

    Content type: Research

    Published on:

  8. The use of an ultrasound-guided technique for radial arterial catheterization has not been well established in pediatric patients. We conducted a systematic review and meta-analysis to evaluate the efficacy of...

    Authors: Wen Zhang, Kunpeng Li, Hui Xu, Dawei Luo, Changbin Ji, Keshi Yang and Qinghua Zhao

    Citation: Critical Care 2020 24:197

    Content type: Research

    Published on:

  9. In order to assess the significance of drug/substance levels measured in intensive care medicine and clinical and forensic toxicology as well as for therapeutic drug monitoring, it is essential that a comprehe...

    Authors: Martin Schulz, Achim Schmoldt, Hilke Andresen-Streichert and Stefanie Iwersen-Bergmann

    Citation: Critical Care 2020 24:195

    Content type: Review

    Published on:

  10. The aim of this review is to describe variation in standards and guidelines on ‘heating, ventilation and air-conditioning (HVAC)’ system maintenance in the intensive care units, across the world, which is requ...

    Authors: Sai Saran, Mohan Gurjar, Arvind Baronia, Vijayalakshmi Sivapurapu, Pralay S. Ghosh, Gautham M. Raju and Indubala Maurya

    Citation: Critical Care 2020 24:194

    Content type: Review

    Published on:

  11. In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinic...

    Authors: Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li and Zhiyong Peng

    Citation: Critical Care 2020 24:188

    Content type: Research

    Published on:

  12. In the publication of this article [1], there was an error in Fig. 1 which caused that the a, b were switched and ‘b’ was missing as a caption on Fig. 1b.

    Authors: Karin Thevissen, Cato Jacobs, Michelle Holtappels, Mitsuru Toda, Paul Verweij and Joost Wauters

    Citation: Critical Care 2020 24:186

    Content type: Correction

    Published on:

    The original article was published in Critical Care 2020 24:84

  13. Arginine vasopressin has complex actions in critically ill patients, involving vasoregulatory status, plasma volume, and cortisol levels. Copeptin, a surrogate marker for arginine vasopressin, has shown promis...

    Authors: Joachim Düring, Martin Annborn, Tobias Cronberg, Josef Dankiewicz, Yvan Devaux, Christian Hassager, Janneke Horn, Jesper Kjaergaard, Michael Kuiper, Homa Rafi Nikoukhah, Pascal Stammet, Johan Undén, Michael Jaeger Wanscher, Matt Wise, Hans Friberg and Niklas Nielsen

    Citation: Critical Care 2020 24:185

    Content type: Research

    Published on:

  14. The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delir...

    Authors: Katarzyna Kotfis, Shawniqua Williams Roberson, Jo Ellen Wilson, Wojciech Dabrowski, Brenda T. Pun and E. Wesley Ely

    Citation: Critical Care 2020 24:176

    Content type: Review

    Published on:

    The Letter to this article has been published in Critical Care 2020 24:375

  15. Arterial blood pressure (BP) is a fundamental cardiovascular variable, is routinely measured in perioperative and intensive care medicine, and has a significant impact on patient management. The clinical refer...

    Authors: Bernd Saugel, Karim Kouz, Agnes S. Meidert, Leonie Schulte-Uentrop and Stefano Romagnoli

    Citation: Critical Care 2020 24:172

    Content type: Review

    Published on:

    The Correction to this article has been published in Critical Care 2020 24:374

  16. Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or ou...

    Authors: Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M. Jakob, Ulrich Jaschinski, Ghaleb A. Almekhlafi, Marc Leone, Majid Mokhtari, Luis E. Fontes, Philippe R. Bauer and Yasser Sakr

    Citation: Critical Care 2020 24:171

    Content type: Research

    Published on:

  17. Dipeptidyl peptidase-3 (DPP3) is a metallopeptidase which cleaves bioactive peptides, notably angiotensin II, and is involved in inflammation regulation. DPP3 has been proposed to be a myocardial depressant fa...

    Authors: François Dépret, Juliette Amzallag, Adrien Pollina, Laure Fayolle-Pivot, Maxime Coutrot, Maïté Chaussard, Karine Santos, Oliver Hartmann, Marion Jully, Alexandre Fratani, Haikel Oueslati, Alexandru Cupaciu, Mourad Benyamina, Lucie Guillemet, Benjamin Deniau, Alexandre Mebazaa…

    Citation: Critical Care 2020 24:168

    Content type: Research

    Published on: