Skip to main content
Fig. 2 | Critical Care

Fig. 2

From: Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery: a prospective observational cohort study

Fig. 2

Derivation classification tree for PERSEVERE-CPB model. The classification tree consists of two biomarker-based decision rules and one clinically based decision rule. The 12-h interleukin-8 (IL8) serum concentration and the change in C-C chemokine ligand 3 (CCL3) serum concentration from 4 to 12 h were included. Each node contains the total number of subjects meeting the biomarker concentration or clinically based decision rule criteria, the number of subjects with or without persistent multiple organ dysfunction syndrome (MODS) at postoperative day (POD) 5, and the percentage of each respective outcome. Terminal nodes 1 and 3 were considered low-risk nodes, with subjects being less likely to develop persistent MODS. Terminal nodes 2 and 4 were considered high-risk and more predictive of development of persistent MODS. The area under the curve (AUC) for this tree was 0.86, with cross-validated estimate for AUROC of 0.75

Back to article page

Critical Care

ISSN: 1364-8535