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Table 1 Baseline characteristics of 814 patients with and without significant persistent pain at 3 months

From: Prevalence and risk factors of significant persistent pain symptoms after critical care illness: a prospective multicentric study

 

No or mild symptoms

N = 426

Significant pain symptoms

N = 388

P value

Gender

Male

301 (70.8%)

240 (62%)

0.01

Female

124 (29.2%)

147 (38%)

Age

58 (± 17)

56 (± 17)

0.2

Height (cm)

171 (± 13)

170 (± 10)

0.1

Weight (kg)

79 (± 19)

81 (± 21)

0.5

Medical history

Hypertension

180 (42.3%)

152 (39.2%)

0.4

Chronic obstructive pulmonary disease

34 (8%)

34 (8.8%)

0.8

Ischemic cardiomyopathy

57 (13.4%)

34 (8.8%)

0.05

Diabetes mellitus

78 (18.3%)

58 (15%)

0.2

History of cancer

91 (21.4%)

74 (19.1%)

0.5

Stroke

12 (2.8%)

12 (3.1%)

0.9

Hypercholesterolemia

79 (18.5%)

61 (15.7%)

0.3

Anxiety and depression syndrome

28 (6.6%)

40 (10.3%)

0.1

Active smoking

109 (25.7%)

102 (26.5%)

0.9

Chronic alcohol intake

62 (14.7%)

66 (17.1%)

0.4

Chronic medication

Paracetamol, NSAID

44 (10.4%)

46 (11.9%)

0.6

Tramadol

14 (3.3%)

19 (4.9%)

0.3

Morphine

15 (3.5%)

19 (4.9%)

0.4

Gabapentin, Pregabalin

19 (4.5%)

25 (6.5%)

0.3

Neuroleptics

22 (5.2%)

30 (7.8%)

0.2

Antidepressant agent

27 (6.4%)

45 (11.8%)

0.01

Cause of admission

 < 0.001

Traumatic brain injury

7 (1.6%)

8 (2%)

 

Stroke

7 (1.6%)

7 (1.8%)

 

Trauma (non neuro)

37 (8.7%)

87 (22.4%)

 

Major thoracic surgery

37 (8.7%)

30 (7.7%)

 

Burn

42 (9.9%)

23 (5.9%)

 

Sepsis

51 (12%)

21 (5.4%)

 

COVID-19

36 (8.5%)

37 (9.5%)

 

Acute respiratory failure

29 (6.8%)

28 (7.2%)

 

Non-thoracic surgery

116 (27.2%)

89 (22.9%)

 

Other

64 (15%)

58 (15%)

 
  1. Chronic pain symptoms were defined as a Numeric Rating Scale ≥ 3, at 3-months after admission. NSAID: Non-Steroidal Anti-Inflammatory Drug. Numeric variables are expressed as mean (± SD). Continuous outcomes were compared with Student's t-test. Discrete outcomes were compared with chi-squared or Fisher’s (£) exact test