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Table 1 Details of data extraction (Part 1)

From: Optimizing enteral nutrition delivery by implementing volume-based feeding protocol for critically ill patients: an updated meta-analysis and systematic review

Author, year

Study type

P.T

N.O.P (ITT)

Proportion of calorie delivery (%)

Completion of 80% energy delivery (n/N)

Proportion of protein delivery (%)

Patients with feeding intolerance (n/N)

VBF

RBF

VBF

RBF

VBF

RBF

VBF

RBF

Daren K Heyland [59]

RCT

ICU patients with mechanical ventilation

519 (252 vs. 267)

43.6 + 32.1

33.6 + 29.5

NM

NM

47.4 + 34.7

33.8 + 29.9

NM

NM

Stephen A. McClave [64]

RCT

Critical patients

57 (37 vs. 20)

92.9 ± 16.8

80.9 ± 18.9

NM

NM

NM

NM

NM

NM

Kate Fetterplace [57]

RCT

Critical patients

60 (30 vs. 30)

84 ± 21

73 ± 11

NM

NM

90 ± 25

57 ± 8

9/30

8/30

Yanxia Lu [52]

RCT

Critical patients

56 (28 vs. 28)

92 ± 80

84 ± 10

NM

NM

NM

NM

NM

NM

Guiyan Qi [53]

RCT

Critical patients with ventilation

120 (60 vs. 60)

77.4 ± 13.8

53.6 ± 13.3

NM

NM

NM

NM

27/60

23/60

Shuangshuang Yang [54]

RCT

ICU patients with mechanical ventilation

121 (61 vs. 60)

93 ± 24

82 ± 18

NM

NM

NM

NM

11/61

7/60

Ivy N. Haskins [58]

Cohort study

Critical patients

77 (39 vs. 38)

74.01

57.02

NM

NM

NM

NM

NM

NM

Susan Roberts [66]

Cohort study

Critical patients

171 (56 vs. 53)

79.6 ± 14.5

67.6 ± 17.8

NM

NM

79.3 ± 13.7

68.6 ± 16.4

NM

NM

Elizabeth D. Krebs [62]

Cohort study

Trauma, burn and surgical critical patients

99 (50 vs. 49)

84.5 (67.5–91.9)

73.4 (58.6–83.6)

NM

NM

86.2 (72.1–93.7)

77.4 (61.0–87.8)

9/50

15/49

Gaurav Sachdev [67]

Cohort study

Trauma critical patients

222 (78 vs. 144)

73.3 ± 13.3

65 ± 15.3

25/78

24/144

NM

NM

NM

NM

JaNae Kinikin [61]

Cohort study

Critical patients

70 (35 vs. 35)

80.9 ± 13.5

66.5 ± 24.0

NM

NM

NM

NM

NM

NM

Amanda Holyk [60]

Cohort study

Critical patients

189 (89 vs. 100)

102.00

75

63/89

42/100

87

68

NM

NM

Mina Bharal [55]

Cohort study

ICU patients with mechanical ventilation

82 (55 vs. 27)

77.8 ± 13.4

46.1 ± 19.7

NM

NM

72.9 ± 15.0

40.1 ± 18.9

5/55

7/27

Travis Swiatlo [68]

Cohort study

Trauma, and surgical critical patients

283 (77 vs. 206)

93.1 ± 11.3

71.3 ± 35.8

NM

NM

NM

NM

NM

NM

Phillip J. Prest [65]

Cohort study

Trauma, and surgical critical patients

492 (295 vs. 197)

NM

NM

1726/3028

678/2523

NM

NM

NM

NM

Angela Bonomo [56]

Cohort study

Surgical critical patients

73 (63 vs. 10)

99.8 (69–108)

67.5 (62–75)

NM

NM

NM

NM

NM

NM

Jason McCartt [63]

Cohort study

Trauma, and surgical critical patients

488 (232 vs. 256)

85.50

75.30

167/232

122/256

NM

NM

52/2059

29/2663