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Table 2 Hemodynamic and respiratory variables during the study protocol

From: The increase in cardiac output induced by a decrease in positive end-expiratory pressure reliably detects volume responsiveness: the PEEP-test study

 

Baseline 1

(n = 64)

PLR (n = 64)

Baseline 2 (n = 64)

PEEP-test (n = 64)

Baseline 3 (n = 64)

Volume expansion (n = 30)

PEEP, mmHg

Volume responsive

Volume unresponsive

13 ± 2

12 ± 3

13 ± 2

12 ± 3

13 ± 2

12 ± 3

5 ± 0

5 ± 0

13 ± 2

12 ± 3

13 ± 2

RR, /min

Volume responsive

Volume unresponsive

26 ± 4

26 ± 5

26 ± 4

26 ± 5

26 ± 4

26 ± 5

26 ± 4

26 ± 5

26 ± 4

26 ± 5

26 ± 4

SpO2, %

Volume responsive

Volume unresponsive

94 ± 2

94 ± 3

94 ± 3

94 ± 3

94 ± 2

94 ± 3

93 ± 4¤

93 ± 4¤

94 ± 3

94 ± 3

96 ± 21

HR, beats/min

Volume responsive

Volume unresponsive

84 ± 21

78 ± 23

83 ± 22

78 ± 22

85 ± 23

79 ± 24

85 ± 23

78 ± 23

85 ± 21

78 ± 23

78 ± 201

SAP, mmHg

Volume responsive

Volume unresponsive

120 ± 25

120 ± 25

134 ± 27*

128 ± 21*

120 ± 25

119 ± 21

130 ± 26¤

125 ± 20¤

120 ± 26

120 ± 21

138 ± 351

DAP, mmHg

Volume responsive

Volume unresponsive

57 ± 13

57 ± 15

62 ± 13*

60 ± 14*

57 ± 12

56 ± 14

59 ± 12¤

57 ± 14¤

56 ± 12

56 ± 14

60 ± 141

MAP, mmHg

Volume responsive

Volume unresponsive

77 ± 16

78 ± 16

87 ± 18*

83 ± 15*

77 ± 16

76 ± 15

83 ± 18¤

80 ± 15¤

77 ± 17

77 ± 14

87 ± 221

PP, mmHg

Volume responsive

Volume unresponsive

61 ± 23

63 ± 23

72 ± 25*

68 ± 19*

63 ± 22

63 ± 18

71 ± 22¤

66 ± 22

64 ± 22

64 ± 18

77 ± 29

 ± 

CVP, mmHg

Volume responsive

Volume unresponsive

9 ± 3

10 ± 4

12 ± 3*

14 ± 4*

8 ± 3

10 ± 4

7 ± 3¤

8 ± 4¤

8 ± 3

10 ± 4

11 ± 31

CI, L/min/m2

Volume responsive

Volume unresponsive

2.4 ± 0.7

2.7 ± 0.7

2.8 ± 0.9*

2.8 ± 0.7

2.4 ± 0.7

2.7 ± 0.7

2.9 ± 0.9¤

2.9 ± 0.7¤

2.4 ± 0.7

2.7 ± 0.7

2.8 ± 0.71

PPV, %

Volume responsive

Volume unresponsive

9 ± 6

7 ± 6

7 ± 6

6 ± 5

10 ± 6

6 ± 4$

6 ± 5¤

6 ± 4

9 ± 6

6 ± 5

6 ± 51

SVV, %

Volume responsive

Volume unresponsive

10 ± 6

8 ± 5

7 ± 6*

6 ± 4*

11 ± 6

6 ± 4$

8 ± 6¤

7 ± 5

10 ± 7

7 ± 5$

7 ± 61

  1. *p < 0.05 PLR vs. Baseline 1
  2. ¤ p < 0.05 PEEP-test vs. Baseline 2
  3. 1 p < 0.05 Volume expansion vs. Baseline 3
  4. $ p < 0.05 responders vs. non-responders
  5. CVP Central venous pressure, CI Cardiac index, DAP Diastolic arterial pressure, HR Heart rate, MAP Mean arterial pressure, PEEP Positive end-expiratory pressure PLR Passive leg raising, PPV Pulse pressure variation, RR Respiratory rate, SAP Systolic arterial pressure, SVV Stroke volume variation
  6. Values are expressed as mean ± standard deviation
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Critical Care

ISSN: 1364-8535