Table 1 Baseline characteristics of subjects according to neurological outcomes at 6 months after cardiac arrest
Good outcome N = 46 | Poor outcome N = 54 | P | |
|---|---|---|---|
Age, years | 53.3 ± 15.5 | 58.3 ± 16.2 | 0.118 |
Sex, male | 39 (84.8) | 39 (72.2) | 0.131 |
Comorbidities | |||
Hypertension | 14 (30.4) | 20 (37.0) | 0.487 |
Diabetes mellitus | 10 (21.7) | 19 (35.2) | 0.140 |
Cardiac cause of arrest | 32 (69.6) | 18 (33.3) | < 0.001 |
Resuscitation variables | |||
Witness | 32 (69.6) | 32 (59.3) | 0.285 |
Bystander CPR | 38 (82.6) | 34 (63.0) | 0.029 |
Initial shockable rhythm | 27 (58.7) | 9 (16.7) | < 0.001 |
Time from collapse to ROSC, min | 24.3 ± 49.9 | 54.4 ± 59.6 | 0.015 |
Post-resuscitation variables | |||
Arterial pH | 7.24 ± 0.12 | 7.16 ± 0.22 | 0.029 |
Lactate, mmol/L | 6.15 ± 3.90 | 9.69 ± 5.23 | 0.001 |
TTM induction time, hour | 5.0 (2.7, 8.3) | 5.0 (3.0, 7.7) | 0.922 |
NSE concentration, ng/mL | |||
0 h | 34.7 (21.5–41.3) | 43.0 (29.3–57.4) | < 0.001 |
24 h | 22.9 (17.2–33.2) | 53.3 (34.2–83.6) | < 0.001 |
48 h | 18.0 (13.9–27.3) | 50.0 (28.9–19.0) | < 0.001 |
72 h | 16.5 (12.3–24.7) | 44.9 (26.8–140.4) | < 0.001 |
S100-B concentration, ng/mL | |||
0 h | 0.33 (0.25–0.82) | 1.54 (0.74–3.56) | 0.001 |
24 h | 0.08 (0.05–0.12) | 0.29 (0.11–5.18) | < 0.001 |
48 h | 0.08 (0.06–0.12) | 0.28 (0.09–2.02) | < 0.001 |
72 h | 0.07 (0.06–0.13) | 0.38 (0.12–1.13) | < 0.001 |