Fig. 7
Dysregulated lipid metabolism in CAP. A Heatmap showing expression levels of apolipoproteins in CONs, S-CAPs, and NS-CAPs. B Representative apolipoprotein expression changes across 3 groups. Square and bars represent the mean and standard deviation, respectively. Statistical significance was determined using the FDR-adjusted p-value. *p < 0.05; **p < 0.01; ***p < 0.001. C The interaction network for apolipoproteins and proteins associated with macrophage function. D Correlation analysis of inflammatory-associated proteins and apolipoproteins. Red and blue numbers represent positive and negative correlation, respectively. * means correlation p value < 0.05. ** means correlation p value < 0.01. E Heatmap of DAMs that are associated with fatty acyls, glycerolipids, glycerophospholipids, prenol lipids, sphingolipids, steroid and steroid derivatives