Variables | Survivors (n = 220) | Non-survivors (n = 35) | p value |
---|---|---|---|
Age (years) (mean ± SD) | 60.21 ± 0.96 | 61.91 ± 2.96 | 0.527 |
Male gender (n, %) | 134 (60.91) | 23 (65.71) | 0.587 |
Comorbidities (n, %) | |||
Arterial hypertension | 102 (46.36) | 13 (37.14) | 0.309 |
Diabetes mellitus | 54 (24.55) | 8 (22.86) | 0.829 |
Chronic heart disease | 30 (13.64) | 5 (14.29) | 0.917 |
Chronic renal failure | 11 (5) | 3 (8.57) | 0.389 |
Immunosuppression | 27 (12.27) | 3 (0.09) | 0.528 |
HIV | 6 (2.73) | 3 (8.57) | 0.082 |
Predisposing conditions (n, %) | |||
Otitis | 85 (38.64) | 7 (20.00) | 0.033 |
Sinusitis | 29 (13.18) | 4 (11.43) | 0.774 |
Vaccine against pneumococcus | 7 (3.18) | 1 (2.86) | 0.918 |
Hospital admission in previous month | 21 (9.55) | 3 (8.57) | 0.855 |
Prior neurological symptomatology | 46 (19.09) | 2 (5.71) | 0.033 |
Clinical data at diagnosis | |||
Glasgow coma score (median, IQR) | 10 (8–12) | 8 (4–9) | < 0.001 |
Glasgow < 8 (indicating coma) (n, %) | 80 (36.36) | 22 (62.86) | 0.003 |
APACHE-II score (median, IQR) | 16 (12–21) | 23 (18–28) | < 0.001 |
SOFA score (median, IQR) | 4 (3–6) | 7 (5–11) | < 0.001 |
SAPS3 score (median, IQR) | 55.5 (46–63) | 64 (48–75) | 0.002 |
Septic shock (n, %) | 28 (12.73) | 11 (31.43) | 0.004 |
Mechanical ventilation (n, %) | 138 (62.73) | 31 (88.57) | 0.003 |
Length of ICU stay (days) (median, IQR) | 7 (4–13) | 5 (2–13) | 0.081 |
Length of hospital stay (days) (median, IQR) | 16 (13–31) | 6 (2–13) | < 0.001 |