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Table 1 Characteristics of the study population

From: Severe community-acquired Streptococcus pneumoniae bacterial meningitis: clinical and prognostic picture from the intensive care unit

Variables

Survivors (n = 220)

Non-survivors (n = 35)

p value

Age (years) (mean ± SD)

60.21 ± 0.96

61.91 ± 2.96

0.527

Male gender (n, %)

134 (60.91)

23 (65.71)

0.587

Comorbidities (n, %)

   

Arterial hypertension

102 (46.36)

13 (37.14)

0.309

Diabetes mellitus

54 (24.55)

8 (22.86)

0.829

Chronic heart disease

30 (13.64)

5 (14.29)

0.917

Chronic renal failure

11 (5)

3 (8.57)

0.389

Immunosuppression

27 (12.27)

3 (0.09)

0.528

HIV

6 (2.73)

3 (8.57)

0.082

Predisposing conditions (n, %)

   

Otitis

85 (38.64)

7 (20.00)

0.033

Sinusitis

29 (13.18)

4 (11.43)

0.774

Vaccine against pneumococcus

7 (3.18)

1 (2.86)

0.918

Hospital admission in previous month

21 (9.55)

3 (8.57)

0.855

Prior neurological symptomatology

46 (19.09)

2 (5.71)

0.033

Clinical data at diagnosis

   

Glasgow coma score (median, IQR)

10 (8–12)

8 (4–9)

< 0.001

Glasgow < 8 (indicating coma) (n, %)

80 (36.36)

22 (62.86)

0.003

APACHE-II score (median, IQR)

16 (12–21)

23 (18–28)

< 0.001

SOFA score (median, IQR)

4 (3–6)

7 (5–11)

< 0.001

SAPS3 score (median, IQR)

55.5 (46–63)

64 (48–75)

0.002

Septic shock (n, %)

28 (12.73)

11 (31.43)

0.004

Mechanical ventilation (n, %)

138 (62.73)

31 (88.57)

0.003

Length of ICU stay (days) (median, IQR)

7 (4–13)

5 (2–13)

0.081

Length of hospital stay (days) (median, IQR)

16 (13–31)

6 (2–13)

< 0.001