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Fig. 1 | Critical Care

Fig. 1

From: Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity

Fig. 1

Complement factors in patients with sepsis. Violin plots of concentrations of the complement factors C3 (a), C3a (b), C3c (c), C5 (d), C5a (e), and sTCC (f) in plasma of patients with sepsis (n = 209) compared to healthy controls (n = 10). Data are presented as median with interquartile range on a log-scale. The P values in the panels were calculated with Mann–Whitney U tests. Heatmaps of the correlations between complement factors (g) and between the complement factors and inflammatory parameters (h). Correlation coefficients and P values were calculated with Spearman rank correlation tests. *Indicates P < 0.05 after Bonferroni correction for multiple testing. Abbreviations: HC, healthy controls; sTCC, soluble terminal complement complex; CRP, C-reactive protein

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